Adjuvancy effects of a RIG-I agonist (RIG101) on H1N1 HA antigen intranasally vaccinated mice and human nasal epithelium/PBMCs co-culture

被引：0
|
作者：
Hassibi, Shyreen [1 ]
Daly, Leah [1 ]
Knowles, Ian [2 ]
Shur, Jag [3 ]
Rapeport, Garth [3 ]
Sobolov, Susan [3 ]
Ito, Kazuhiro [1 ]
机构：
[1] Imperial Coll London, London, England
[2] Pharmidex, London, England
[3] RIGImmune Inc, Farmington, CT USA
来源：
EUROPEAN RESPIRATORY JOURNAL | 2024年 / 64卷
关键词：
D O I：
10.1183/13993003.congress-2024.OA3678
中图分类号：
R56 [呼吸系及胸部疾病];
学科分类号：
摘要：
引用
收藏
页数：2
相关论文
共 4 条
  • [1] Pan-antiviral effects of RIG-I agonist (RIG-101) against respiratory syncytial virus and human rhinovirus in nasal epithelium in vitro and mice in vivo
    Daly, Leah
    Moen, Agnethe
    Ombredane, Hugo
    Knowles, Ian
    Shur, Jag
    Rapeport, Garth
    Sobolov, Susan
    Ito, Kazuhiro
    EUROPEAN RESPIRATORY JOURNAL, 2024, 64
  • [2] 5′-TRIPHOSPHATE DSRNA-INDUCED STIMULATION OF RIG-I PREVENTS INFLUENZA H1N1 INFECTION OF PRIMARY NASAL EPITHELIAL CELL CULTURE AND PROTECTS MICE FROM INFECTION IN VIVO
    Coch, C.
    Stehle, V
    Kuemmerer, B.
    Stabenow, D.
    Stuempel, J. P.
    Dassler, J.
    Herberhold, S.
    Luedenbach, B.
    Kochs, G.
    Staeheli, P.
    Bootz, F.
    Schlee, M.
    Hartmann, E.
    Hartmann, G.
    NUCLEIC ACID THERAPEUTICS, 2011, 21 (05) : A48 - A48
  • [3] Influenza A(H1N1)pdm09 Virus Suppresses RIG-I Initiated Innate Antiviral Responses in the Human Lung
    Wu, Wenxin
    Zhang, Wei
    Booth, J. Leland
    Metcalf, Jordan P.
    PLOS ONE, 2012, 7 (11):
  • [4] Human Eosinophils Reduce Viral Titer, Secrete IL-8, and Increase RIG-I Expression in Response to Influenza A H1N1 pdm09
    Flores-Torres, Armando S.
    Rendon, Adrian
    Salinas-Carmona, Mario C.
    Salinas, Eva
    Rosas-Taraco, Adrian G.
    VIRAL IMMUNOLOGY, 2021, 34 (08) : 573 - 578
1