Identification and Characterization of Novel NLRP3 Inflammasome Inhibitors for the Potential Treatment of Retinal Disease

被引:0
|
作者
Rodriguez, Mirna [1 ]
Meng, Frank [1 ]
Bishop, Michael [2 ]
Perlroth, D. Victor [1 ]
Liang, Hong [1 ]
Jandeleit, Bernd [1 ]
Williams, Kim [1 ]
机构
[1] Kodiak Sci, Palo Alto, CA USA
[2] Bishop Drug Discovery Consulting LLC, San Diego, CA USA
关键词
D O I
暂无
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
2208
引用
收藏
页数:2
相关论文
共 50 条
  • [1] Novel inhibitors of the NLRP3 inflammasome
    Fulp, Jacob
    He, Liu
    Jiang, Yuqi
    Zhang, Shijun
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2017, 254
  • [2] Development of novel NLRP3 inflammasome inhibitors and their potential application
    Zhang, Shijun
    Chojnacki, Jeremy
    Marchetti, Carlo
    Toldo, Stefano
    Abbate, Antonio
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2015, 249
  • [3] Novel Aryl Sulfonamide Derivatives as NLRP3 Inflammasome Inhibitors for the Potential Treatment of Cancer
    Albanese, Valentina
    Missiroli, Sonia
    Perrone, Mariasole
    Fabbri, Martina
    Boncompagni, Caterina
    Pacifico, Salvatore
    De Ventura, Tiziano
    Ciancetta, Antonella
    Dondio, Giulio
    Kricek, Franz
    Pinton, Paolo
    Guerrini, Remo
    Preti, Delia
    Giorgi, Carlotta
    JOURNAL OF MEDICINAL CHEMISTRY, 2023, 66 (07) : 5223 - 5241
  • [4] Saponins as potential novel NLRP3 inflammasome inhibitors for inflammatory disorders
    Tang, Jiamei
    Liu, Yaxiao
    Wu, Ying
    Li, Shixing
    Zhang, Dongdong
    Wang, Haifang
    Wang, Wei
    Song, Xiaomei
    Li, Yuze
    ARCHIVES OF PHARMACAL RESEARCH, 2024, 47 (10-11) : 757 - 792
  • [5] Chalcone: A potential scaffold for NLRP3 inflammasome inhibitors
    Thapa, Pritam
    Upadhyay, Sunil P.
    Singh, Vikas
    Boinpelly, Varun C.
    Zhou, Jianping
    Johnson, David K.
    Gurung, Prajwal
    Lee, Eung Seok
    Sharma, Ram
    Sharma, Mukut
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY REPORTS, 2023, 7
  • [6] Cardioprotective effects of novel NLRP3 inflammasome inhibitors
    Comita, Stefano
    Pagliaro, Pasquale
    Penna, Claudia
    Bertinaria, Massimo
    Spyrakis, Francesca
    Gastaldi, Simone
    Boscaro, Valentina
    Gianquinto, Eleonora
    JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 2022, 173 : S123 - S124
  • [7] Pharmacological Inhibitors of the NLRP3 Inflammasome
    Zahid, Ayesha
    Li, Bofeng
    Kombe, Arnaud John Kombe
    Jin, Tengchuan
    Tao, Jinhui
    FRONTIERS IN IMMUNOLOGY, 2019, 10
  • [8] Promise of the NLRP3 Inflammasome Inhibitors in In Vivo Disease Models
    Das, Biswadeep
    Sarkar, Chayna
    Rawat, Vikram Singh
    Kalita, Deepjyoti
    Deka, Sangeeta
    Agnihotri, Akash
    MOLECULES, 2021, 26 (16):
  • [9] Phytochemical inhibitors of the NLRP3 inflammasome for the treatment of inflammatory diseases
    Ozenver, Nadire
    Efferth, Thomas
    PHARMACOLOGICAL RESEARCH, 2021, 170
  • [10] Development of Novel Tetrahydroquinoline Inhibitors of NLRP3 Inflammasome for Potential Treatment of DSS-Induced Mouse Colitis
    Dai, Zhen
    Chen, Xiao-Yi
    An, Lu-Yan
    Li, Cui-Cui
    Zhao, Ni
    Yang, Fan
    You, Song-Tao
    Hou, Chen-Zhi
    Li, Kan
    Jiang, Cheng
    You, Qi-dong
    Di, Bin
    Xu, Li-Li
    JOURNAL OF MEDICINAL CHEMISTRY, 2021, 64 (01) : 871 - 889