Foundational insights for theranostic applications of magnetoelectric nanoparticles

被引：0

作者：

Andre, Victoria ^{[1
]}

Abdel-Mottaleb, Mostafa ^{[1
]}

Shotbolt, Max ^{[1
]}

Chen, Shawnus ^{[2
]}

Ramezini, Zeinab ^{[3
]}

Zhang, Elric ^{[3
]}

Conlan, Skye ^{[1
]}

Telisman, Ozzie ^{[4
]}

Liang, Ping ^{[5
]}

Bryant, John M. ^{[6
]}

Chomko, Roman ^{[7
]}

Khizroev, Sakhrat ^{[3
,8
]}

机构：

[1] Univ Miami, Dept Biomed Engn, Coral Gables, FL USA

[2] Univ Miami, Dept Chem Environm & Mat Engn, Coral Gables, FL USA

[3] Univ Miami, Dept Elect & Comp Engn, Coral Gables, FL 33146 USA

[4] Univ Miami, Dept Chem, Coral Gables, FL USA

[5] Cellular Nanomed, Irvine, CA USA

[6] H Lee Moffitt Canc Ctr & Res Inst, Tampa, FL USA

[7] Univ Calif Riverside, Dept Elect & Comp Engn, Riverside, CA USA

[8] Univ Miami, Dept Biochem & Mol Biol, Miami Project Cure Paralysis, Miami, FL 33146 USA

来源：

NANOSCALE HORIZONS | 2025年

基金：

美国国家卫生研究院; 美国国家科学基金会;

关键词：

NEXT-GENERATION; BARIUM-TITANATE; DELIVERY; SURFACE; DRUG; ELECTROPORATION; NANOCARRIERS; BRAIN;

D O I：

10.1039/d4nh00560k

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Reviewing emerging biomedical applications of MagnetoElectric NanoParticles (MENPs), this paper presents basic physics considerations to help understand the possibility of future theranostic applications. Currently emerging applications include wireless non-surgical neural modulation and recording, functional brain mapping, high-specificity cell electroporation for targeted cancer therapies, targeted drug delivery, early screening and diagnostics, and others. Using an ab initio analysis, each application is discussed from the perspective of its fundamental limitations. Furthermore, the review identifies the most eminent challenges and offers potential engineering solutions on the pathway to implement each application and combine the therapeutic and diagnostic capabilities of the nanoparticles.

引用

页数：20

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