CAR-T Therapy Versus Bispecific Antibodies in Relapsed Refractory Multiple Myeloma: Systematic Review and Metanalysis of Toxicity and Response

被引：0
|
作者：
Mehta, Mansi [1 ]
Namjoshi, Devang [1 ]
Fernandes, Bolivia Crocete Aloysia [2 ,3 ]
Mukhtiar, Vaibhavi [1 ]
Bhanushali, Charmi [1 ]
Kumar, Madhan Srinivasan [4 ]
Rana, Gunjan [1 ]
Santhi, Jaison Lawrence Alexander [5 ]
Mishra, Tanisha [6 ]
Ramanathan, Muthalagu [7 ,8 ]
机构：
[1] St Vincent Hosp, Worcester, MA, Brazil
[2] St Marys Gen Hosp, New York Med Coll, Grad Med Educ Program, Denville, NJ USA
[3] St Clares Hlth, Denville, NJ USA
[4] St Vincent Hosp, Internal Med, Worcester, MA, Brazil
[5] Mercy Catholic Med Ctr, Aldan, PA USA
[6] Manipal Acad Higher Educ, Kasturba Med Coll, Manipal, India
[7] Univ Massachusetts, Mem Med Ctr, Dept Med, Div Hematol Oncol, Worcester, MA, Brazil
[8] UMass Mem Med Ctr, Div Stem Cell Transplantat, Worcester, MA, Brazil
来源：
BLOOD | 2024年 / 144卷
关键词：
D O I：
10.1182/blood-2024-206207
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页码：6929 / 6930
页数：2
相关论文
共 50 条
  • [1] Bispecific Antibodies as Bridging to BCMA CAR-T Cell Therapy for Relapsed/Refractory Multiple Myeloma
    Fandrei, David
    Seiffert, Sabine
    Rade, Michael
    Rieprecht, Susanne
    Gagelmann, Nico
    Born, Patrick
    Wiemers, Thomas
    Weidner, Heike
    Kreuz, Markus
    Schassberger, Tamara
    Kossmann, Jannik
    Mangold, Marlene
    Fuerst, Daniel
    Fischer, Luise
    Baber, Ronny
    Heyn, Simone
    Wang, Song Yau
    Bach, Enrica
    Hoffmann, Sandra
    Metzeler, Klaus H.
    Herling, Marco
    Jentzsch, Madlen
    Franke, Georg-Nikolaus
    Koehl, Ulrike
    Friedrich, Maik
    Boldt, Andreas
    Reiche, Kristin
    Platzbecker, Uwe
    Vucinic, Vladan
    Merz, Maximilian
    BLOOD CANCER DISCOVERY, 2025, 6 (01): : 38 - 54
  • [2] CAR-T Therapy in Relapsed Refractory Multiple Myeloma
    Ding, Hong
    Wu, Yu
    CURRENT MEDICINAL CHEMISTRY, 2024, 31 (27) : 4362 - 4382
  • [3] Bispecific Antibodies Improve Outcomes in Patients With Relapsed or Refractory Multiple Myeloma After Car-T Cell Therapy
    Merz, Maximilan
    Dima, Danai
    Hashmi, Hamza
    Mueller, Fabian
    Ahmed, Nausheen
    Rathje, Kristin
    Davis, James
    Holderried, Tobias
    Vucinik, Vladan
    Kharbouti, Soraya
    Ayuk, Francis
    Stoelzel, Friedrich
    Schub, Natalie
    Schmitz, Friederike
    Shune, Leyla
    Khouri, Jack
    Anwer, Faiz
    McGuirk, Joseph
    Teichert, Marcel
    von Tresckow, Bastian
    Kroeger, Nicolaus
    Pabst, Thomas
    Abdallah, Al-Ola
    Gagelmann, Nico
    CLINICAL LYMPHOMA MYELOMA & LEUKEMIA, 2024, 24 : S73 - S74
  • [4] The Role of Bispecific Antibodies in Relapsed Refractory Multiple Myeloma: A Systematic Review
    Khanam, Razwana
    Ashruf, Omer S.
    Bin Waqar, Syed Hamza
    Shah, Zunairah
    Batool, Saba
    Mehreen, Rameesha
    Pachika, Pranali
    Roksana, Zinath
    Rehman, Mohammad Ebad Ur
    Anwer, Faiz
    ANTIBODIES, 2023, 12 (02)
  • [5] CAR-T and Bispecific Antibodies: The New Standard for Relapsed and Refractory Multiple Myeloma, or Reserved for Late-Line Salvage Therapy?
    Rodriguez-Otero, Paula
    Martin, Thomas
    HEMATO, 2024, 5 (02): : 171 - 179
  • [6] A Bcma and CD19 Bispecific CAR-T for Relapsed and Refractory Multiple Myeloma
    Zhang, Hua
    Gao, Lei
    Liu, Li
    Wang, Jishi
    Wang, Sanbin
    Gao, Li
    Zhang, Cheng
    Liu, Yao
    Kong, Peiyan
    Liu, Jia
    He, Jiaping
    Han, Yu
    Shi, Hua
    He, Yan
    Ye, Xun
    Zhao, Yi
    Cao, Wei
    Shen, Lianjun
    Zhang, Xi
    BLOOD, 2019, 134
  • [7] A bispecific CAR-T cell therapy targeting BCMA and CD38 in relapsed or refractory multiple myeloma
    Mei, Heng
    Li, Chenggong
    Jiang, Huiwen
    Zhao, Xinying
    Huang, Zhiping
    Jin, Dan
    Guo, Tao
    Kou, Haiming
    Liu, Lin
    Tang, Lu
    Yin, Ping
    Wang, Zhihui
    Ai, Lisha
    Ke, Sha
    Xia, Yimeng
    Deng, Jun
    Chen, Lei
    Cai, Li
    Sun, Chunyan
    Xia, Linghui
    Hua, Gaoquan
    Hu, Yu
    JOURNAL OF HEMATOLOGY & ONCOLOGY, 2021, 14 (01)
  • [8] A bispecific CAR-T cell therapy targeting BCMA and CD38 in relapsed or refractory multiple myeloma
    Heng Mei
    Chenggong Li
    Huiwen Jiang
    Xinying Zhao
    Zhiping Huang
    Dan Jin
    Tao Guo
    Haiming Kou
    Lin Liu
    Lu Tang
    Ping Yin
    Zhihui Wang
    Lisha Ai
    Sha Ke
    Yimeng Xia
    Jun Deng
    Lei Chen
    Li Cai
    Chunyan Sun
    Linghui Xia
    Gaoquan Hua
    Yu Hu
    Journal of Hematology & Oncology, 14
  • [9] Sequential Administration of Selinexor and CAR-T Therapy in Relapsed/ Refractory Multiple Myeloma
    Gill, Sarvarinder Kaur
    Biran, Noa
    Phull, Pooja
    Vesole, David H.
    Siegel, David S.
    Parmar, Harsh
    BLOOD, 2023, 142
  • [10] CAR-T cell therapy in relapsed or refractory multiple myeloma and access in Turkey
    Hakan, Goker
    Engin, Kelkitli
    Elifcan, Karakulak Aladag
    Haluk, Demiroglu
    Mehmet, Turgut
    Suman, Kambhampati
    Maxwell, Krem
    FRONTIERS IN MEDICINE, 2024, 11
12345