Discovery of Nelutroctiv (CK-136), a Selective Cardiac Troponin Activator for the Treatment of Cardiovascular Diseases Associated with Reduced Cardiac Contractility (vol 67, pg 7825, 2024)

被引：0

作者：

Romero, Antonio

Ashcraft, Luke

Chandra, Aroop ^{[1
,2
]}

Dimassa, Vincent ^{[1
,3
]}

Cremin, Peadar ^{[1
,4
]}

Collibee, Scott E.

Chuang, Chihyuan

Hartman, James

Hwee, Darren T.

St. Jean, David ^{[5
,6
]}

Malinowski, Justin ^{[5
,7
]}

Debenedetto, Mikkel ^{[5
,8
]}

Moebius, David C. ^{[5
,9
]}

Payette, Joshua ^{[5
]}

Vargas, Richard ^{[5
]}

Yeoman, John ^{[5
]}

Motani, Alykhan ^{[5
]}

Reagan, Jeffrey ^{[5
]}

Malik, Fady I.

Morgan, Bradley P.

机构：

[1] Cytokinetics Inc, South San Francisco, CA 94080 USA

[2] Cort Agrisci, Indianapolis, IN 46268 USA

[3] Univ Nevada, Reno, NV USA

[4] Circle Pharm, South San Francisco, CA USA

[5] Amgen Inc, Cambridge, MA 02141 USA

[6] Scorp Therapeut, South San Francisco, CA USA

[7] Regeneron Pharmaceut, Tarrytown, NY USA

[8] Sanofi, Cambridge, MA USA

[9] Moderna Therapeut, Cambridge, MA USA

来源：

关键词：

D O I：

10.1021/acs.jmedchem.4c02850

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：850 / 850

页数：1

共 1 条