Extraction and assessment of antifungal properties of natural products from the culture medium of Trichoderma sp. 18F0056

被引：0

作者：

Cheng, Ming-Jen ^{[1
]}

Chen, Jih-Jung ^{[2
,3
,4
]}

Liu, Hsia-Wei ^{[1
,5
]}

Wu, Ming-Der ^{[6
]}

Wei, Yu-Hui ^{[6
]}

Liou, Guey-Yuh ^{[6
]}

Tseng, Min ^{[6
]}

机构：

[1] Fu Jen Catholic Univ, Dept Life Sci, New Taipei City 242, Taiwan

[2] Natl Yang Ming Chiao Tung Univ NYCU, Sch Pharmaceut Sci, Dept Pharm, Taipei 112304, Taiwan

[3] China Med Univ, China Med Univ Hosp, Dept Med Res, Taichung 404333, Taiwan

[4] Taipei Med Univ Hosp, Tradit Herbal Med Res Ctr, Taipei 110, Taiwan

[5] Fu Jen Catholic Univ, Grad Inst Appl Sci & Engn, New Taipei City 242, Taiwan

[6] Food Ind Res & Dev Inst, Bioresource Collect & Res Ctr, Hsinchu 300193, Taiwan

来源：

PHYTOCHEMISTRY LETTERS | 2025年 / 65卷

关键词：

Chromone; Antifungal; Secondary metabolites;

D O I：

10.1016/j.phytol.2024.10.009

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Two previously undescribed chromone derivatives, 1 and 2 , were isolated from the EtOAc-soluble fraction of the culture broth of Trichoderma sp. 18F0056. Their structures were elucidated on the basis of extensive analyses of spectroscopic data and comparison with literature data. Their antifungal activity was also evaluated. Our results showed that both constituents possessed weak antifungal activity against Fusarium sp. LC8, Neopestalotiopsis sp. BCRC 35002, and Colletotrichum gloeosporioides BCRC 35178. In the past, chromone derivatives were rarely found from the genus Trichoderma. This time, the research on the products of this new species of Trichoderma is of significant significance. Trichoderma natural products deserve further evaluation as anti-fungal agents for biocontrol.

引用

页码：44 / 47

页数：4

共 7 条

[1] Metabolites from the Soil-Derived Fungus Trichoderma sp. BCRC-18F0056
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Hsia-Wei Liu
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Chemistry of Natural Compounds, 2025, 61 (2) : 278 - 280
[2] Isolation and antifungal activity assessment of natural compounds from the culture medium of actinobacterium Streptomyces sp. BC129-2
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PHYTOCHEMISTRY LETTERS, 2024, 64 : 1 - 5
[3] Natural products from the culture broth of an actinobacteria Streptomyces sp. M5205 and evaluation of their antifungal activity
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[5] Antifungal compounds with anticancer potential from Trichoderma sp. P8BDA1F1, an endophytic fungus from Begonia venosa
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[6] Antifungal compounds with anticancer potential from Trichoderma sp. P8BDA1F1, an endophytic fungus from Begonia venosa
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[7] A new peptaibol, RK-026A, from the soil fungus Trichoderma sp. RK10-F026 by culture condition-dependent screening
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