Host cell protein impurities are not a relevant driver of gene therapyassociated immune response

被引:0
|
作者
Seitz, Immanuel Philipp [1 ]
Bocanegra, Eduardo [1 ]
Reichel, Felix [1 ,2 ]
Michalakis, Stylianos [3 ]
Biel, Martin [3 ]
Bartz-Schmidt, Karl Ulrich [1 ]
Peters, Tobias [1 ]
Fischer, M. Dominik [1 ,2 ]
机构
[1] Univ Klinikum Tubingen, Ctr Ophthalmol, Tubingen, Baden Wurttembe, Germany
[2] Oxford Eye Hosp, Oxford, Oxon, England
[3] Ctr Integrated Prot Sci, Munich, Bayern, Germany
关键词
D O I
暂无
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
5345
引用
收藏
页数:3
相关论文
共 50 条
  • [1] Experience with Host Cell Protein Impurities in Biopharmaceuticals
    Vanderlaan, Martin
    Zhu-Shimoni, Judith
    Lin, Sansan
    Gunawan, Feny
    Waerner, Thomas
    Van Cott, Kevin E.
    BIOTECHNOLOGY PROGRESS, 2018, 34 (04) : 828 - 837
  • [2] Difficult-to-remove CHO host cell protein impurities
    Lee, Kelvin
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2017, 253
  • [3] Assessment of the immunogenicity of residual host cell protein impurities of OsrHSA
    Abiri, Naghmeh
    Pang, Jianlei
    Ou, Jiquan
    Shi, Bo
    Wang, Xianghong
    Zhang, Sucai
    Sun, Yunxia
    Yang, Daichang
    PLOS ONE, 2018, 13 (03):
  • [4] Methods for addressing host cell protein impurities in biopharmaceutical product development
    Tuameh, Abdulrahman
    Harding, Stephen E.
    Darton, Nicholas J.
    BIOTECHNOLOGY JOURNAL, 2023, 18 (03)
  • [5] Host Cell Autophagy in Immune Response to Zoonotic Infections
    Skendros, Panagiotis
    Mitroulis, Ioannis
    CLINICAL & DEVELOPMENTAL IMMUNOLOGY, 2012,
  • [6] A gene expression map of host immune response in human brucellosis
    Mitroulis, Ioannis
    Chrysanthopoulou, Akrivi
    Divolis, Georgios
    Ioannidis, Charalampos
    Ntinopoulou, Maria
    Tasis, Athanasios
    Konstantinidis, Theocharis
    Antoniadou, Christina
    Soteriou, Natalia
    Lallas, George
    Mitka, Stella
    Lesche, Mathias
    Dahl, Andreas
    Gembardt, Stephanie
    Panopoulou, Maria
    Sideras, Paschalis
    Wielockx, Ben
    Coskun, Uenal
    Ritis, Konstantinos
    Skendros, Panagiotis
    FRONTIERS IN IMMUNOLOGY, 2022, 13
  • [7] Alphacoronavirus Protein 7 Modulates Host Innate Immune Response
    Cruz, Jazmina L. G.
    Becares, Martina
    Sola, Isabel
    Carlos Oliveros, Juan
    Enjuanes, Luis
    Zuniga, Sonia
    JOURNAL OF VIROLOGY, 2013, 87 (17) : 9754 - 9767
  • [8] Chromatographic properties of host cell protein impurities in downstream purification of monoclonal antibodies
    Levy, Nicholas E.
    Valente, Kristin N.
    Lee, Kelvin H.
    Lenhoff, Abraham M.
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2013, 245
  • [9] Monitoring process-related impurities in biologics–host cell protein analysis
    Katrine Pilely
    Martin Rask Johansen
    Rikke Raaen Lund
    Thomas Kofoed
    Thomas Kjærsgaard Jørgensen
    Lars Skriver
    Ejvind Mørtz
    Analytical and Bioanalytical Chemistry, 2022, 414 : 747 - 758
  • [10] Host cell protein impurities in chromatographic polishing steps for monoclonal antibody purification
    Levy, Nicholas E.
    Valente, Kristin N.
    Lee, Kelvin H.
    Lenhoff, Abraham M.
    BIOTECHNOLOGY AND BIOENGINEERING, 2016, 113 (06) : 1260 - 1272