Deletion of epithelial HKDC1 decelerates cellular proliferation and impairs mitochondrial function of tumorous epithelial cells thereby protecting from intestinal carcinogenesis

被引：0
|
作者：
Jaerke, Lea [1 ]
Weber-Stiehl, Saskia [1 ]
Shima, Kensuke [2 ]
Moors, Karlis Arturs [3 ]
Genth, Jerome [3 ]
Schuran, Fenja Amrei [1 ]
Best, Lena [3 ]
Tschurtschenthaler, Markus [4 ,5 ,6 ,7 ,8 ]
Flemer, Burkhardt [1 ]
Lueschen, Silke [9 ]
Roecken, Christoph [9 ]
Tholey, Andreas [3 ]
Kaleta, Christoph [3 ]
Rupp, Jan [2 ,10 ,11 ]
Rosenstiel, Philip [1 ]
Sommer, Felix [1 ]
机构：
[1] Univ Kiel, Inst Clin Mol Biol, Kiel, Germany
[2] Univ Lubeck, Inst Med Microbiol, Lubeck, Germany
[3] Univ Kiel, Inst Expt Med, Kiel, Germany
[4] Tech Univ Munich, Translat Canc Res, Munich, Germany
[5] Tech Univ Munich, Inst Expt Canc Therapy, Sch Med & Hlth, Klinikum Rechts Isar, Munich, Germany
[6] Tech Univ Munich, Ctr Translat Canc Res TranslaTUM, Sch Med & Hlth, Klinikum Rechts Isar, Munich, Germany
[7] German Canc Res Ctr, Div Translat Canc Res, Heidelberg, Germany
[8] German Canc Consortium DKTK, Heidelberg, Germany
[9] Univ Hosp Schleswig Holstein, Dept Pathol, Campus Kiel, Kiel, Germany
[10] Univ Hosp Schleswig Holstein, Infect Dis Clin, Campus Lubeck, Lubeck, Germany
[11] German Ctr Infect Res DZ, Partner Site Hamburg Lubeck Borstel Riems, Lubeck, Germany
来源：
CANCER COMMUNICATIONS | 2025年
关键词：
D O I：
10.1002/cac2.70022
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
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页数：6
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