Hepatitis B virus infections in pregnant women and children in the era of HBV elimination

被引：0
|
作者：
Pawlowska, Malgorzata [1 ]
机构：
[1] Nicolaus Copernicus Univ Torun, Dept Infect Dis & Hepatol, Coll Med Bydgoszcz, Torun, Poland
来源：
CLINICAL AND EXPERIMENTAL HEPATOLOGY | 2024年 / 10卷 / 04期
关键词：
HBV; vertical infections; prevention; occult HBV infections; children;
D O I：
10.5114/ceh.2024.145364
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
In the hepatitis B virus (HBV) elimination strategy announced by the World Health Organization (WHO) in 2016, one of the main aspects is the prevention of vertical infections. In the prevention of vertical HBV infections, chemoprophylaxis with tenofovir is recommended from the 28th week of pregnancy in women with a high viral load (HBV DNA > 2 x 10(5) IU/ml) or the presence of HBeAg in the serum and active-passive immunoprophylaxis (HepB-BD+ HBIG) in all newborns born to mothers infected with HBV. Attention was paid to the incidence of latent HBV infections among children and adolescents and the role of the vaccine dose and additional hepatitis B booster vaccination in the prevention of HBV, especially in highly endemic areas and risk groups. The role of the age of initiation of therapy in the context of functional cure was indicated.
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页码：227 / 231
页数：5
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