Lateral skull-base osteoradionecrosis: a 15-year series of 20 consecutive cases and a suggested management protocol

被引:0
|
作者
Richards, Emma [1 ]
Muzaffar, Jameel [1 ]
Kumar, Raghu [1 ]
Monksfield, Peter [1 ]
Irving, Richard [1 ]
机构
[1] Univ Hosp Birmingham NHS Fdn Trust, Queen Elizabeth Hosp Birmingham, ENT Dept, Birmingham, England
关键词
head and neck neoplasms; temporal bone; radiology; radiotherapy; osteoradionecrosis; TEMPORAL BONE; NECROSIS; DIAGNOSIS; HEAD;
D O I
10.1017/S002221512400077X
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 ;
摘要
Background Temporal bone osteoradionecrosis is a rare but significant complication of radiation for head and neck malignancies. Various management techniques have been described, but no clear protocol exists. Methods A retrospective case review of patients with temporal bone osteoradionecrosis managed over 15 years was carried out to highlight multidisciplinary team (MDT) management. The review findings were compared with the published literature and a protocol was derived for the management of future cases. Results A total of 20 patients were included. The sites of osteoradionecrosis included the external auditory canal, the middle ear and the lateral skull base, presenting with features including recalcitrant pain, infection, neuropathies and intracranial sepsis. Treatments included hyperbaric oxygen, antibiotics, debridement and, in advanced cases, lateral temporal bone resection with vascularised tissue transfer. Post-operative and long-term outcomes were discussed. Conclusion Early temporal bone osteoradionecrosis may be managed conservatively. Refractory osteoradionecrosis can be life-threatening because of intracranial complications and sepsis. Such cases need an MDT approach with radical skull-base surgery for removal of necrotic foci and reconstruction using vascularised tissue transfer.
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