MR-Guided PET Reconstruction

被引：0
|
作者：
Huellner, Martin W. [1 ]
Maurer, Alexander [1 ]
Spangler-Bickell, Matthew [2 ]
机构：
[1] Univ Zurich, Univ Hosp Zurich, Dept Nucl Med, Raemistr 100, CH-8091 Zurich, Switzerland
[2] GE Healthcare, Waukesha, WI USA
来源：
CLINICAL NUCLEAR MEDICINE | 2025年 / 50卷 / 03期
关键词：
epilepsy; seizure; mesiotemporal sclerosis; F-18-FDG; PET/CT; image reconstruction; F-18-FDG PET; EPILEPSY;
D O I：
10.1097/RLU.0000000000005631
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
We report a case of a 33-year-old man with epilepsy and equivocal EEG, MRI signs of mesiotemporal sclerosis, and nondiagnostic standard FDG-PET imaging. The patient underwent repeat FDG-PET/MRI to clarify the sidedness of the epileptogenic focus and to confirm the suspected MTS. The standard PET reconstruction using block sequential regularized expectation maximization failed to provide evidence of a clear epileptogenic focus. However, using MR-guided PET reconstruction, circumscribed hypometabolism was observed in the right-sided entorhinal cortex, compatible with the epileptogenic focus. The MR-guided PET reconstruction provided significantly improved gray/white matter differentiation, enhancing confidence in imaging interpretation.
引用
收藏
页码：271 / 272
页数：2
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