Euphraticanoids N-T: Aromadendrane-Type Diterpenes and Sesquiterpenes with Fungicidal Activities from Populus euphratica Resins

被引：0

作者：

Jiang, Qinbin ^{[1
,2
]}

Liu, Yun-Yun ^{[2
]}

Huang, Danling ^{[2
]}

Cheng, Yong-Xian ^{[1
,2
]}

机构：

[1] Guangdong Pharmaceut Univ, Sch Pharm, Guangzhou 510006, Peoples R China

[2] Shenzhen Univ, Inst Inheritance Based Innovat Chinese Med, Guangdong Prov Key Lab Chinese Med Ingredients & G, Sch Pharm, Shenzhen 518055, Peoples R China

来源：

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | 2025年 / 26卷 / 05期

关键词：

<italic>Populus euphratica</italic> resins; prenylaromadendrane-type diterpenes; aromadendrane-type sesquiterpenes; fungicidal activity;

D O I：

10.3390/ijms26052187

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Seven previously undescribed terpenoids, including five prenylaromadendrane-type diterpenes euphraticanoids N-R (1-5) and two aromadendrane-type sesquiterpenes, euphraticanoids S and T (6 and 7), were isolated from Populus euphratica resins. Their structures, including their absolute configurations, were elucidated by HRESIMS and spectroscopic analysis, ECD calculations, and crystallographic methods. In addition, an evaluation of the fungicidal activities of compound 1 was carried out, resulting in the discovery of 1 as a fungicidal candidate lead compound with an EC50 of 15.7 and 68.6 mg/L against Curvularia mebaldsii and Fusarium graminearum, respectively.

引用

页数：10