A dual-response ratiometric near-infrared fluorescence probe based on cyanine platform for Cu2+ detection and its imaging in vitro and vivo

被引：0

作者：

Chang, Zhijian ^{[1
]}

Li, Shumeng ^{[2
]}

Ye, Jia-Hai ^{[1
]}

Lin, Fuyan ^{[1
]}

Chen, Yuncong ^{[2
]}

Guo, Zijian ^{[2
]}

He, Weijiang ^{[2
]}

机构：

[1] Nanjing Univ Sci & Technol, Sch Chem & Chem Engn, Nanjing 210094, Peoples R China

[2] Nanjing Univ, Sch Chem & Chem Engn, State Key Lab Coordinat Chem, Nanjing 210093, Peoples R China

来源：

SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY | 2025年 / 325卷

基金：

中国国家自然科学基金;

关键词：

Near-infrared probe; Cu2+; Ratiometric; Cyanine derivative; Bioimaging; COPPER; AGGREGATION; SENSOR; LIGHT; CHEMOSENSOR; MICROSCOPY; DISEASE; DESIGN; IONS; NIR;

D O I：

10.1016/j.saa.2024.125115

中图分类号：

O433 [光谱学];

学科分类号：

0703 ; 070302 ;

摘要：

A near-infrared fluorescent probe (NUST-Cy-1) was disclosed here, which displays ratiometric and dual-channel response for Cu2+ (lambda( ex1) = 450 nm, lambda( ex2) = 750 nm) with large Stokes shifts (143 nm, 375 nm, 75 nm respectively). This probe demonstrates high sensitivity with low detection limit (1.4 mu M) and selectivity for Cu2+ detection. Furthermore, fluorescent imaging of Cu2+ in vitro and vivo were successfully achieved.

引用

页数：9

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