CXCL12 Derived From ACKR1+ Intraplaque Neovessels Mediates CD8+ T Cell Recruitment in Human Atherosclerosis

被引：0

作者：

Parma, Laura ^{[1
,2
]}

Sachs, Nadja ^{[2
,3
]}

Sobczak, Nikola ^{[1
]}

Li, Zhaolong ^{[3
]}

Merchant, Kevin ^{[1
,2
]}

Pauli, Jessica ^{[3
]}

Depuydt, Marie A. C. ^{[4
]}

Wezel, Anouk ^{[5
]}

Smeets, Harm J. ^{[5
]}

Bot, Ilze ^{[4
]}

Sluetter, Bram ^{[4
]}

Maegdefessel, Lars ^{[6
]}

Weber, Christian ^{[1
,2
,7
,8
]}

Duchene, Johan ^{[1
,2
]}

Megens, Remco T. A. ^{[1
,2
,3
,7
]}

机构：

[1] Ludwig Maximilians Univ Munchen, Inst Cardiovasc Prevent IPEK, Pettenkoferstr 8a & 9, D-80336 Munich, Germany

[2] German Ctr Cardiovasc Res, Partner Site Munich Heart Alliance, Munich, Germany

[3] Tech Univ Munich, Dept Vasc & Endovasc Surg, Klinikum Rechts Isar, Munich, Germany

[4] Leiden Univ, Leiden Acad Ctr Drug Res, Div BioTherapeut, Leiden, Netherlands

[5] Haaglanden Med Ctr Westeinde, Dept Surg, The Hague, Netherlands

[6] Karolinska Inst, Ctr Mol Med, Dept Med, Stockholm, Sweden

[7] Univ Maastricht, Cardiovasc Res Inst Maastricht, Maastricht, Netherlands

[8] Munich Cluster Syst Neurol, Munich, Germany

来源：

CIRCULATION | 2025年 / 151卷 / 08期

关键词：

atherosclerosis; CD8-positive T-lymphocytes; endothelial cells; microscopy; plaque; atherosclerotic; receptors; chemokine; single-cell gene expression analysis;

D O I：

10.1161/CIRCULATIONAHA.124.072560

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：581 / 584

页数：4

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