Complex Visual Hallucinations Associated With Ranolazine Treatment

Ranolazine is a piperazine derivative and is indicated for the symptomatic treatment of patients with stable angina pectoris who are inadequately controlled by or intolerant to first-line antianginal therapies. Visual hallucinations together with neurologic symptoms have been described with ranolazine treatment. In this case report, we describe a case of an elderly diabetic patient with chronic angina pectoris who developed visual hallucinations during an acute worsening of kidney function after tolerating ranolazine well for 6 years. Regular monitoring of electrocardiograms, kidney function, and psychiatric and neurologic adverse effects in elderly patients on ranolazine is advised.