A flow system featuring a circumferentially impinging jet distributor (CIJD) coupled with coiled tubes was designed for high-throughput excellent mixing. The study investigated the effects of channel Reynolds number (Re-c), pore Reynolds number (Re-p), and Dean number (Dn) on the single-phase flow and different-scale mixing characteristics. Five flow regimes in the CIJD were identified at the range of 3.16 <= Re-c <= 316.3, including separated flow, squeezed flow, symmetric four-vortex flow, transitional flow, and asymmetric four-vortex flow. High-energy impinging jets promoted vortex entrainment, expanding the fluid contact interface. The extension of leg vortices and the emergence of secondary vortex pairs effectively enhanced mixing. As Re-c further increased, the concentration distribution in the CIJD tended to be uniform and challenging to quantify. Therefore, micro-mixing time t(m) = 0.97-58.4 ms was determined using the Villermaux-Dushman reaction system at the ranges of 177.2 <= Re-c <= 1063.4 and 265.3 <= Re-p <= 1591.6, and its correlation was established. Tracer pulse-response technique was employed to measure residence time distribution and P & eacute;clet numbers (Pe = 9.1-191.1) in the flow system at the range of 3.0 <= Dn <= 1797.4. The axial dispersion was analyzed from the perspectives of diffusion-dominated and convection-dominated on radial mixing. This easily regulated flow system, in which single-phase flow and multi-scale mixing are comprehensively characterized, holds practical value for mass transfer and reaction process intensification.
