The COVID-19 pandemic gave rise to the need for social isolation, causing the closing of schools, which, in order not to stop their activities, adhered to the remote teaching format. This format required a reconfiguration of classes and teaching methodologies adopted by teachers, bringing, consequently, numerous challenges. In this context, this research aimed to identify the challenges faced by teachers for remote teaching of Mathematics during the COVID-19 pandemic. Therefore, a Systematic Literature Review was carried out in articles published between 2020 and 2021. Data were analyzed using a quantitative approach. As results, it was evident that the Mathematics teachers used several tools for remote teaching, the most recurrent being the videoconference platforms, the WhatsApp application and video classes on YouTube. It was also found that the main challenges to the teaching activity in remote Mathematics classes are the limited access to the internet and digital technologies by the students, as well as the difficulty in dealing with technology by the teachers, especially given the quantity considerable number of professionals who did not have access to the necessary training to work in remote learning.