Activating the dark genome to illuminate cancer vaccine targets

被引：0
|
作者：
Kwok, Darwin W. [1 ]
Okada, Hideho [1 ,2 ]
Costello, Joseph F. [1 ]
机构：
[1] Univ Calif San Francisco, Dept Neurol Surg, San Francisco, CA 94143 USA
[2] Parker Inst Canc Immunotherapy, San Francisco, CA 94129 USA
来源：
NATURE GENETICS | 2024年 / 56卷 / 09期
关键词：
DNA METHYLATION; GENES;
D O I：
暂无
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
Epigenetic therapy triggers myriad transposable elements to generate new antigens that could prime tumor cells for immunotherapy. A study of glioblastoma discovers indiscriminate activation in healthy cells as well, and presents a more selective strategy for potential therapeutic targeting.
引用
收藏
页码：1770 / 1771
页数：2
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