High-Pressure Extraction Techniques for Efficient Recovery of Flavonoids and Coumarins from Flower Seeds

The extraction of bioactive compounds, such as flavonoids and coumarins, from natural sources has gained significant attention due to their potential health benefits. This review aims to explore the application of high-pressure extraction processes, particularly supercritical fluid extraction (SFE) and pressurized liquid extraction (PLE), for obtaining flavonoids and coumarins from flower seeds. These techniques offer a greener, more efficient alternative to conventional extraction methods, minimizing the use of harmful solvents and improving the yield and purity of the target compounds. Flower seeds, a rich source of bioactive molecules, are an underutilized reservoir for these valuable compounds. For example, seeds from plants such as Calendula officinalis (calendula) and Helianthus annuus (sunflower) are rich in flavonoids and coumarins. The proposed review will examine the influence of extraction parameters-such as temperature, pressure, solvent choice, and extraction time-on the yield and quality of flavonoids and coumarins. This review aims to provide a comprehensive understanding of high-pressure extraction methods and optimize protocols for the efficient, sustainable extraction of flavonoids and coumarins from flower seeds.