The stability of soil in high-altitude regions is significantly affected by freeze-thaw cycles, which alter its mechanical and physical properties. This study investigates the impact of 12 consecutive freeze-thaw cycles on poorly graded sandy-silt soil collected from Arunachal Pradesh. To enhance soil resistance, a bio-slurry containing urea (60 g/L) and calcium chloride (111 g/L), along with vetiver and bamboo fibers (by soil weight), was introduced as a stabilizing agent. The durability of the treated soil was evaluated by measuring the weight fluctuations after each cycle and assessing unconfined compressive strength (UCS) after 5, 10, and 12 cycles. The results revealed that untreated soil experienced a 50% reduction in UCS, while bioslurry-treated soil retained 70-80% of its original strength after 12 freeze-thaw cycles. The greatest strength retention was observed in soil treated with bioslurry and bamboo fiber, which retained 80% of its strength, followed by vetiver-treated soil at 75% strength retention. Weight loss measurements indicated that untreated soil samples lost 9.5% of their initial mass, whereas bioslurry-treated samples exhibited only a 3-5% weight loss. The findings of the study highlight the potential of bioslurry and natural fibers in mitigating freeze-thaw-induced soil degradation, making them suitable for applications in geotechnical engineering in cold-climate regions.