PERIPHERAL BLOCKADE OF CB1 SIGNALING IMPROVES LIVER FIBROSIS

被引：0
|
作者：
Ishizuka, Kei [1 ]
Ganguly, Souradipta [2 ]
Das, Barun [2 ]
Nindra, Malika [2 ]
Bhattacharya, Aryaman [2 ]
Kisseleva, Tatiana [2 ]
Ikejima, Kenichi [3 ]
Brenner, David [4 ]
Dhar, Debanjan [4 ]
机构：
[1] Juntendo Univ, Grad Sch Med, Tokyo, Japan
[2] Univ Calif San Diego, San Diego, CA 92103 USA
[3] Juntendo Univ, Sch Med, Tokyo, Japan
[4] Sanford Burnham Prebys Med Discovery Inst, San Diego, CA USA
来源：
HEPATOLOGY | 2024年 / 80卷
关键词：
D O I：
暂无
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
130
引用
收藏
页码：S84 / S85
页数：2
相关论文
共 50 条
  • [1] Peripheral CB1 cannabinoid receptor blockade improves cardiometabolic risk in mouse models of obesity
    Tam, Joseph
    Vemuri, V. Kiran
    Liu, Jie
    Batkai, Sandor
    Mukhopadhyay, Bani
    Godlewski, Grzegorz
    Osei-Hyiaman, Douglas
    Ohnuma, Shinobu
    Ambudkar, Suresh V.
    Pickel, James
    Makriyannis, Alexandros
    Kunos, George
    JOURNAL OF CLINICAL INVESTIGATION, 2010, 120 (08): : 2953 - 2966
  • [2] The peripheral CB1 receptor antagonist JD5037 attenuates liver fibrosis via a CB1 receptor/β-arrestin1/Akt pathway
    Tan, Siwei
    Liu, Huiling
    Ke, Bilun
    Jiang, Jie
    Wu, Bin
    BRITISH JOURNAL OF PHARMACOLOGY, 2020, 177 (12) : 2830 - 2847
  • [3] Reduced liver fibrosis in CB1 receptor knockout mice
    Grenard, P
    Julien, B
    Tran-Van-Nhieu, J
    Li, L
    Ledent, C
    Mallat, A
    Lotersztajn, S
    JOURNAL OF HEPATOLOGY, 2004, 40 : 8 - 8
  • [4] SELECTIVE BLOCKADE OF PERIPHERAL CB1 RECEPTORS IS EFFECTIVE IN THE TREATMENT OF OBESITY AND BOTH NONALCOHOLIC AND ALCOHOLIC FATTY LIVER
    Tam, J.
    Cinar, R.
    Chorvat, R. J.
    McElroy, J. F.
    Kunos, G.
    ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH, 2011, 35 (06) : 303A - 303A
  • [5] CB1 Blockade Activates Sirt1 and AMPK Signaling to Improve Glycemic Control and Increase Energy Expenditure in the Liver
    Liu, Jie
    Godlewski, Grzegorz
    Jourdan, Tony
    Xiong, Keming
    Cinar, Resat
    Lin, Yuhong
    Liu, Ziyi
    Kunos, George
    DIABETES, 2016, 65 : A67 - A67
  • [6] Central and peripheral consequences of the chronic blockade of CB1 cannabinoid receptor with rimonabant or taranabant
    Martin-Garcia, Elena
    Burokas, Aurelijus
    Martin, Miquel
    Berrendero, Fernando
    Rubi, Blanca
    Kiesselbach, Christoph
    Heyne, Andrea
    Domingo Gispert, Juan
    Millan, Olga
    Maldonado, Rafael
    JOURNAL OF NEUROCHEMISTRY, 2010, 112 (05) : 1338 - 1351
  • [7] Peripheral CB1 receptor blockade acts as a memory enhancer through a noradrenergic mechanism
    Martinez-Torres, Sara
    Bergada-Martinez, Araceli
    Ortega, Jorge E.
    Galera-Lopez, Lorena
    Hervera, Arnau
    de los Reyes-Ramirez, Lucia
    Ortega-Alvaro, Antonio
    Remmers, Floortje
    Munoz-Moreno, Emma
    Soria, Guadalupe
    del Rio, Jose Antonio
    Lutz, Beat
    Ruiz-Ortega, Jose Angel
    Meana, J. Javier
    Maldonado, Rafael
    Ozaita, Andres
    NEUROPSYCHOPHARMACOLOGY, 2023, 48 (02) : 341 - 350
  • [8] Peripheral CB1 receptor blockade acts as a memory enhancer through a noradrenergic mechanism
    Sara Martínez-Torres
    Araceli Bergadà-Martínez
    Jorge E. Ortega
    Lorena Galera-López
    Arnau Hervera
    Lucía de los Reyes-Ramírez
    Antonio Ortega-Álvaro
    Floortje Remmers
    Emma Muñoz-Moreno
    Guadalupe Soria
    José Antonio del Río
    Beat Lutz
    Jose Ángel Ruíz-Ortega
    J. Javier Meana
    Rafael Maldonado
    Andrés Ozaita
    Neuropsychopharmacology, 2023, 48 : 341 - 350
  • [9] Signaling of CB1 receptors in astrocytes
    Marsicano, G.
    JOURNAL OF NEUROCHEMISTRY, 2019, 150 : 31 - 31
  • [10] CB1 cannabinoid receptor antagonism: a new strategy for the treatment of liver fibrosis
    Teixeira-Clerc, Fatima
    Julien, Boris
    Grenard, Pascale
    Van Nhieu, Jeanne Tran
    Deveaux, Vanessa
    Li, Liying
    Serriere-Lanneau, Valerie
    Ledent, Catherine
    Mallat, Ariane
    Lotersztajn, Sophie
    NATURE MEDICINE, 2006, 12 (06) : 671 - 676
12345