SYNTHESIS OF NOVEL LIPOIC ACID DERIVATIVES

被引:0
|
作者
Gonzalez-gutierrez, Juan pablo [1 ]
Moris, S. [2 ]
Barrientos, C. [2 ]
机构
[1] Univ Autonoma Chile, Fac Ingn, Inst Ciencias Aplicadas, Providencia, Chile
[2] Univ Catolica Maule, Ctr Invest Estudios Avanzados Maule CIEAM, Vicerrectoria Invest & Postgrad, Talca, Chile
来源
关键词
Steglich esterification; Lipoic derivatives;
D O I
暂无
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Lipoic acid is a naturally occurring compound involved in biological processes with special reactivity due to its 1,2-dithiolane ring. The novel ALA derivatives were synthesized using the Steglich esterification in mild conditions and then concentrated and neutralized with yields of 45.1 to 81.2%.
引用
收藏
页码:6054 / 6055
页数:2
相关论文
共 50 条
  • [1] Novel synthesis of lipoic acid derivatives for biosynthetic pathways
    Johnson, Jorden A.
    Olson, Andrew
    Dussault, Patrick
    Moreau, Regis
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2014, 247
  • [2] LIPOIC ACID .I. SYNTHESIS OF RACEMIC LIPOIC ACID AND ITS DERIVATIVES
    TURSIN, VM
    CHEBOTAR.LG
    FILONOVA, LM
    POPOVA, SM
    PREOBRAZ.NA
    JOURNAL OF GENERAL CHEMISTRY USSR, 1964, 34 (11): : 3711 - &
  • [3] Synthesis and anticancer evaluation of α-lipoic acid derivatives
    Zhang, Shi-Jie
    Ge, Qiu-Fu
    Guo, Dian-Wu
    Hu, Wei-Xiao
    Liu, Hua-Zhang
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2010, 20 (10) : 3078 - 3083
  • [4] Synthesis and characterization of new and potent α-lipoic acid derivatives
    Gruzman, A
    Hidmi, A
    Katzhendler, J
    Haj-Yehie, A
    Sasson, S
    BIOORGANIC & MEDICINAL CHEMISTRY, 2004, 12 (05) : 1183 - 1190
  • [5] Synthesis and Biological Activity of Lipoic Acid Ester Derivatives
    Zhang Luyun
    Xu Qian
    Xia Guangqing
    Cong Li
    Wang Yu
    Zhang Hui
    Zhu Junyi
    Zang Hao
    CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE, 2018, 39 (10): : 2198 - 2205
  • [6] Synthesis and characterization of selenotrisulfide-derivatives of lipoic acid and lipoamide
    Self, WT
    Tsai, L
    Stadtman, TC
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2000, 97 (23) : 12481 - 12486
  • [7] Synthesis and characterization of α-lipoic acid grafted chitosan derivatives with antioxidant activity
    Tan, Wenqiang
    Zhang, Jingjing
    Mi, Yingqi
    Li, Qing
    Guo, Zhanyong
    REACTIVE & FUNCTIONAL POLYMERS, 2022, 172
  • [8] Novel 1,3,4-thiadiazol derivatives including α-lipoic acid: Synthesis, characterization, and antioxidant properties
    Bakir, Temel Kan
    Ashweeqi, Mohammed Ali Abraheem
    Muglu, Halit
    JOURNAL OF MOLECULAR STRUCTURE, 2024, 1307
  • [9] BIOSYNTHESIS AND STRUCTURE OF LIPOIC ACID DERIVATIVES
    GUNSALUS, IC
    BARTON, LS
    GRUBER, W
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1956, 78 (08) : 1763 - 1766
  • [10] PREPARATION AND ASSAY OF LIPOIC ACID AND DERIVATIVES
    GUNSALUS, IC
    RAZZELL, WE
    METHODS IN ENZYMOLOGY, 1957, 3 : 941 - 946