IDENTIFICATION AND TARGETING OF TUMOR DRIVER SCHWANN(NF2LOSS) CELLS IN SPORADIC AND NF2-RELATED VESTIBULAR SCHWANNOMAS

被引:0
|
作者
Laws, Maxwell [1 ]
Asuzu, David [1 ]
Rampalli, Ihika [1 ]
Mullaney, Dustin [1 ]
Laraba, Liyam [2 ]
Mandel, Debjani [1 ]
Zhang, Xiyuan [3 ]
Elkahloun, Abdel [4 ]
Sisay, Bayu [4 ]
Maric, Dragan [5 ]
Johnson, Kory [6 ]
Abdullaev, Zied [7 ]
Aldape, Kenneth [7 ]
Shern, John [3 ]
Parkinson, David [2 ]
Chittiboina, Prashant [1 ]
机构
[1] Natl Inst Neurol Disorders & Stroke, NIH, Surg Neurol Branch, Bethesda, MD USA
[2] Plymouth Univ, Sch Med & Dent, Plymouth, England
[3] NCI, NIH, Ctr Canc Res, Pediat Oncol Branch,Tumor Evolut & Genom Sect, Bethesda, MD USA
[4] Natl Human Genome Res Inst, NIH, Canc Genet & Comparat Genom Branch, Bethesda, MD USA
[5] Natl Inst Neurol Disorders & Stroke, NIH, Flow & Imaging Cytometry Core Facil, Bethesda, MD USA
[6] Natl Inst Neurol Disorders & Stroke, NIH, DIR Bioinformat Sect, Bethesda, MD USA
[7] NCI, NIH, Lab Pathol, Bethesda, MD USA
关键词
D O I
10.1093/neuonc/noae165.0268
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
CSIG-19
引用
收藏
页数:1
相关论文
共 50 条
  • [1] Genetic Alterations in Patients with NF2-Related Schwannomatosis and Sporadic Vestibular Schwannomas
    Douwes, Jules P. J.
    van Eijk, Ronald
    Maas, Sybren L. N.
    Jansen, Jeroen C.
    Aten, Emmelien
    Hensen, Erik F.
    CANCERS, 2025, 17 (03)
  • [2] Therapy of Sporadic and NF2-Related Vestibular Schwannoma
    Yao, Longping
    Alahmari, Mohammed
    Temel, Yasin
    Hovinga, Koos
    CANCERS, 2020, 12 (04)
  • [3] ACTIVITY OF BEVACIZUMAB AGAINST NF2-RELATED VESTIBULAR SCHWANNOMAS
    Plotkin, Scott
    Halpin, Christopher
    Stemmer-Rachamimov, Anat
    Barker, Fred
    Sorensen, Gregory
    Jain, Rakesh
    Di Tomaso, Emmanuelle
    NEURO-ONCOLOGY, 2008, 10 (05) : 796 - 796
  • [4] INTRATUMORAL CONCENTRATION AND MOLECULAR PHARMACODYNAMICS OF LAPATINIB IN VIVO IN SPORADIC AND NF2-RELATED VESTIBULAR SCHWANNOMAS
    Karajannis, Matthias
    Bergner, Amanda
    Giovannini, Marco
    Welling, D. Bradley
    Niparko, John
    Slattery, William
    Roland, J. Thomas
    Golfinos, John
    Allen, Jeffrey
    Blakeley, Jaishri
    NEURO-ONCOLOGY, 2012, 14 : 19 - 19
  • [5] Correlation between VEGF expression and MVD in sporadic and NF2-related schwannomas
    Ditomaso, E.
    Stemmer-Rachamimov, A.
    Potts, A.
    Drottar, M.
    Jain, R. K.
    Plotkin, S. R.
    JOURNAL OF CLINICAL ONCOLOGY, 2007, 25 (18)
  • [6] Proton Radiotherapy for Vestibular Schwannomas in Patients with NF2-Related Schwannomatosis: A Case Series
    Douwes, Jules P. J.
    Koetsier, Kimberley S.
    van Dam, Victor S.
    Plotkin, Scott R.
    Barker, Frederick G.
    Welling, D. Bradley
    Jansen, Jeroen C.
    Hensen, Erik F.
    Shih, Helen A.
    CURRENT ONCOLOGY, 2023, 30 (03) : 3473 - 3483
  • [7] The comparable tumour microenvironment in sporadic and NF2-related schwannomatosis vestibular schwannoma
    Gregory, Grace E.
    Jones, Adam Paul
    Haley, Michael J.
    Hoyle, Christopher
    Zeef, Leo A. H.
    Lin, I-Hsuan
    Coope, David J.
    King, Andrew T.
    Evans, D. Gareth
    Paszek, Pawel
    Couper, Kevin N.
    Brough, David
    Pathmanaban, Omar N.
    BRAIN COMMUNICATIONS, 2023, 5 (04)
  • [8] Four distinct ipsilateral vestibular schwannomas: A case of mosaic NF2-related schwannomatosis
    Tunkel, Alexandra E.
    Youner, Emily R.
    Barseghyan, Hayk
    Fu, Yulong
    Bhattacharya, Surajit
    Bornhorst, Miriam
    Monfared, Ashkan S.
    AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 2024, 162 (02) : 110 - 114
  • [9] Hearing preservation and tumour control after radiosurgery for NF2-related vestibular schwannomas
    Massager, N.
    Delbrouck, C.
    Masudil, J.
    De Smedt, F.
    Devriendt, D.
    B-ENT, 2013, 9 (01): : 29 - 36
  • [10] Rates of loss of heterozygosity and mitotic recombination in NF2 schwannomas, sporadic vestibular schwannomas and schwannomatosis schwannomas
    Hadfield, K. D.
    Smith, M. J.
    Urquhart, J. E.
    Wallace, A. J.
    Bowers, N. L.
    King, A. T.
    Rutherford, S. A.
    Trump, D.
    Newman, W. G.
    Evans, D. G.
    ONCOGENE, 2010, 29 (47) : 6216 - 6221