Identification of allosteric inhibitors targeting Discoidin Domain Receptor 2 (DDR2)

被引:0
|
作者
Cano, S. [1 ]
Carrillo, J. [1 ]
Alvarez, D. [1 ]
Barril, X. [1 ]
Cubero, E. [1 ]
Belloto, M. [2 ]
Garcia-Collazo, A. M. [1 ]
Perez-Carmona, N. [1 ]
Taylor, J. [3 ]
机构
[1] Gain Therapeut Sucursal Espan, Res Dept, Barcelona, Spain
[2] Gain Therapeut SA, Res Dept, Lugano, Switzerland
[3] Gain Therapeut Inc, Res Dept, Bethesda, MD USA
关键词
D O I
10.1016/j.ejca.2024.114564
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
36
引用
收藏
页码:S16 / S16
页数:1
相关论文
共 50 条
  • [1] Expression of discoidin domain receptor 2 (DDR2) in the developing heart
    Morales, MO
    Price, RL
    Goldsmith, EC
    MICROSCOPY AND MICROANALYSIS, 2005, 11 (03) : 260 - 267
  • [2] The discoidin domain receptor DDR2 is a receptor for type X collagen
    Leitinger, Birgit
    Kwan, Alvin P. L.
    MATRIX BIOLOGY, 2006, 25 (06) : 355 - 364
  • [3] Discoidin domain receptor 2 (DDR2) localization and function in the developing heart
    Hoffman, A
    Morales, M
    Jacobs, A
    Potts, JD
    Price, RL
    Borg, TK
    Goldsmith, EC
    MOLECULAR BIOLOGY OF THE CELL, 2002, 13 : 64A - 64A
  • [4] Discoidin domain receptor 2 (DDR2) regulates proliferation of endochondral cells in mice
    Kawai, Ikuma
    Hisaki, Tomoka
    Sugiura, Koji
    Naito, Kunihiko
    Kano, Kiyoshi
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2012, 427 (03) : 611 - 617
  • [5] Discoidin Domain Receptor 2 (DDR2) Is Required for Maintenance of Spermatogenesis in Male Mice
    Kano, Kiyoshi
    Kitamura, Ayami
    Matsuwaki, Takashi
    Morimatsu, Masami
    Naito, Kunihiko
    MOLECULAR REPRODUCTION AND DEVELOPMENT, 2010, 77 (01) : 29 - 37
  • [6] Prognostic significance of discoidin domain receptor 2 (DDR2) expression in ovarian cancer
    Fan, Yi
    Xu, Zhe
    Fan, Jin
    Huang, Liu
    Ye, Ming
    Shi, Kun
    Huang, Zheng
    Liu, Yaqiong
    He, Langchi
    Huang, Jiezhen
    Wang, Yibin
    Li, Qiufeng
    AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH, 2016, 8 (06): : 2845 - 2850
  • [7] DDR2, a discoidin domain receptor, is a marker of periosteal osteoblast and osteoblast progenitors
    Haili Yang
    Lei Sun
    Wenqian Cai
    Jingkai Gu
    Dacai Xu
    Arjun Deb
    Jinzhu Duan
    Journal of Bone and Mineral Metabolism, 2020, 38 : 670 - 677
  • [8] The intracellular juxtamembrane domain of discoidin domain receptor 2 (DDR2) is essential for receptor activation and DDR2-mediated cancer progression
    Kim, Daehwan
    Ko, Panseon
    You, Eunae
    Rhee, Sangmyung
    INTERNATIONAL JOURNAL OF CANCER, 2014, 135 (11) : 2547 - 2557
  • [9] DDR2, a discoidin domain receptor, is a marker of periosteal osteoblast and osteoblast progenitors
    Yang, Haiti
    Sun, Lei
    Cai, Wenqian
    Gu, Jingkai
    Xu, Dacai
    Deb, Arjun
    Duan, Jinzhu
    JOURNAL OF BONE AND MINERAL METABOLISM, 2020, 38 (05) : 670 - 677
  • [10] Targeting of Discoidin Domain Receptor 2 (DDR2) Prevents Myofibroblast Activation and Neovessel Formation During Pulmonary Fibrosis
    Zhao, Hu
    Bian, Huan
    Bu, Xin
    Zhang, Shuya
    Zhang, Pan
    Yu, Jiangtian
    Lai, Xiaofeng
    Li, Di
    Zhu, Chuchao
    Yao, Libo
    Su, Jin
    MOLECULAR THERAPY, 2016, 24 (10) : 1734 - 1744