SYNTHESIS AND SPECTROSCOPIC CHARACTERIZATION OF TRIDENTATE LIGANDS AND THEIR ANTIMICROBIAL BIOLOGICAL STUDIES

被引：0
|
作者：
Bansod, Ashish D. [1 ]
机构：
[1] Rajarshee Shahu Sci Coll Chandur Rly, Dept Chem, Amravati, India
来源：
HETEROCYCLIC LETTERS | 2024年 / 14卷 / 04期
关键词：
Pyrazine-2-carbohydrazone; Biological Activity; COMPLEXES;
D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Schiff base ligand synthesized by condensation of pyrazine-2-carbohydrazide with 1-(5chloro-2-hydroxyphenyl) ethan-1-one,1-(2-hydroxy-phenyl) ethan-1-one and 1-(2-hydroxy-5methylphenyl) ethan-1-one were characterized by elemental analyses, magnetic susceptibility measurements, IR, reflectance spectra, thermal analysis, powder X- ray diffraction and SEM analysis. The Schiff base ligands were screened in vitro for their biological activity against E. coli MTCC 443, P. aeruginosa MTCC 424, S. aureus MTCC 96, B. subtilis MTCC 8979, E. faecalis MTCC 439andS. pyogenes MTCC 442 and fungal strains, C. albicans MTCC 227, A. niger MTCC 282 and A. clavatus MTCC 1323 and all the ligands. Showed better biological efficacy.
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页码：757 / 763
页数：7
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