Research progress in OX40/OX40L in allergic diseases

被引：0
|
作者：
Song, Rongrong [1 ]
Zhang, Huanlei [1 ]
Liang, Zhuoping [1 ]
机构：
[1] Southwest Med Univ, Affiliated Hosp, Dept Otolaryngol Head & Neck Surg, 25 Taiping St, Luzhou 646000, Sichuan, Peoples R China
来源：
INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY | 2024年 / 14卷 / 12期
关键词：
allergic rhinitis; asthma; atopic dermatitis; OX40; OX40L; ATOPIC-DERMATITIS; RHINITIS; QUESTIONS; BLOCKADE;
D O I：
10.1002/alr.23469
中图分类号：
R76 [耳鼻咽喉科学];
学科分类号：
100213 ;
摘要：
OX40/OX40L are costimulatory molecules in the tumor necrosis factor superfamily. Numerous studies have shown that OX40/OX40L are involved in immune regulation, especially in the proliferation and differentiation of T cells and the generation of memory T cells, which play important roles in allergic diseases. In recent years, the use of OX40/OX40L as therapeutic targets for treating T-cell-mediated diseases has attracted the interest of scholars. This paper reviews the role of OX40/OX40L in allergic diseases and the progress in clinical treatments targeting this signaling pathway.
引用
收藏
页码：1921 / 1928
页数：8
相关论文
共 50 条
  • [1] OX40/OX40L in RA
    John Isaacs
    Arthritis Research & Therapy, 3 (1)
  • [2] OX40/OX40L与疾病
    刘纯
    王玉亮
    医学综述, 2011, 17 (15) : 2271 - 2273
  • [3] Characterisation of chicken OX40 and OX40L
    Scherer, Stephanie
    Goebel, Thomas W.
    DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 2018, 82 : 128 - 138
  • [4] OX40 and OX40L Interaction in Cancer
    Lu, Xinjie
    CURRENT MEDICINAL CHEMISTRY, 2021, 28 (28) : 5659 - 5673
  • [5] OX40/OX40L axis: not a friend in autoimmunity
    Ueno, Hideki
    Blanco, Patrick
    ONCOTARGET, 2015, 6 (26) : 21779 - 21780
  • [6] OX40/OX40L与T细胞
    卢凯
    陈明
    东南大学学报(医学版), 2012, 31 (03) : 355 - 358
  • [7] OX40, OX40L and Autoimmunity: a Comprehensive Review
    Webb, Gwilym J.
    Hirschfield, Gideon M.
    Lane, Peter J. L.
    CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY, 2016, 50 (03) : 312 - 332
  • [8] OX40, OX40L and Autoimmunity: a Comprehensive Review
    Gwilym J. Webb
    Gideon M. Hirschfield
    Peter J. L. Lane
    Clinical Reviews in Allergy & Immunology, 2016, 50 : 312 - 332
  • [9] OX40 (CD134) and OX40L
    Gough, Michael J.
    Weinberg, Andrew D.
    THERAPEUTIC TARGETS OF THE TNF SUPERFAMILY, 2009, 647 : 94 - 107
  • [10] The role of OX40/OX40L axis in atopic dermatitis
    Yamamura, K.
    Yamamura, M.
    Garcet, S.
    Dahabreh, D.
    Gonzalez, J.
    Miura, S.
    Williams, S.
    Nakahara, T.
    Krueger, J.
    Guttman-Yassky, E.
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2023, 143 (05) : S11 - S11
12345