The mitochondrial citrate carrier SLC25A1 is a regulator of metabolic reprogramming and morphogenesis in the developing heart

被引:0
|
作者
Ohanele, Chiemela
Peoples, Jessica
Karlstaedt, Anja
Geiger, Joshua
Ghazal, Nasab
Brown, Milton
Davis, Michael
Porter, George
Kwong, Jennifer
机构
关键词
D O I
10.1161/res.135.suppl_1.We087
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
We087
引用
收藏
页数:2
相关论文
共 45 条
  • [1] The mitochondrial citrate carrier SLC25A1 regulates metabolic reprogramming and morphogenesis in the developing heart
    Ohanele, Chiemela
    Peoples, Jessica N.
    Karlstaedt, Anja
    Geiger, Joshua T.
    Gayle, Ashley D.
    Ghazal, Nasab
    Sohani, Fateemaa
    Brown, Milton E.
    Davis, Michael E.
    Porter Jr, George A.
    Faundez, Victor
    Kwong, Jennifer Q.
    COMMUNICATIONS BIOLOGY, 2024, 7 (01)
  • [2] The citrate carrier SLC25A1 acts as regulator of metabolic reprogramming offering an innovative strategy for synthetic lethality approaches with radiotherapy
    Xiang, K.
    Kalthoff, C.
    Jendrossek, V.
    Matschke, J.
    STRAHLENTHERAPIE UND ONKOLOGIE, 2022, 198 (SUPPL 1) : S152 - S153
  • [3] The citrate carrier SLC25A1 acts as master regulator of metabolic reprogramming and offers an innovative strategy for metabolic induction of HRness and synthetic lethality approaches with radiotherapy.
    Xiang, K.
    Kalthoff, C.
    Muench, C.
    Hlouschek, J.
    Jendrossek, V.
    Matschke, J.
    STRAHLENTHERAPIE UND ONKOLOGIE, 2021, 197 (SUPPL 1) : S48 - S49
  • [4] The Mitochondrial Citrate Carrier SLC25A1/CIC and the Fundamental Role of Citrate in Cancer, Inflammation and Beyond
    Mosaoa, Rami
    Kasprzyk-Pawelec, Anna
    Fernandez, Harvey R.
    Avantaggiati, Maria Laura
    BIOMOLECULES, 2021, 11 (02) : 1 - 17
  • [5] A key role of the mitochondrial citrate carrier (SLC25A1) in TNFα- and IFNγ-triggered inflammation
    Infantino, Vittoria
    Iacobazzi, Vito
    Menga, Alessio
    Avantaggiati, Maria Laura
    Palmieri, Ferdinando
    BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS, 2014, 1839 (11): : 1217 - 1225
  • [6] SLC25A1 regulates placental development to ensure embryonic heart morphogenesis
    Fan, Wenli
    Li, Zixuan
    He, Xueke
    Wang, Xiaodong
    Sun, Ming
    Yang, Zhongzhou
    DEVELOPMENT, 2024, 151 (22):
  • [7] Inhibition of the mitochondrial citrate carrier SLC25A1 induces a DNA repair defect and increases cancer cell radiosensitivity
    Kalthoff, C.
    Hlouschek, J.
    Koska, B.
    Vuellings, M.
    Timmermann, B.
    Jendrossek, V
    Matschke, J.
    STRAHLENTHERAPIE UND ONKOLOGIE, 2020, 196 (SUPPL 1) : S184 - S184
  • [8] The mitochondrial citrate carrier, SLC25A1, drives stemness and therapy resistance in non-small cell lung cancer
    Harvey R. Fernandez
    Shreyas M. Gadre
    Mingjun Tan
    Garrett T. Graham
    Rami Mosaoa
    Martin S. Ongkeko
    Kyu Ah Kim
    Rebecca B. Riggins
    Erika Parasido
    Iacopo Petrini
    Simone Pacini
    Amrita Cheema
    Rency Varghese
    Habtom W Ressom
    Yuwen Zhang
    Christopher Albanese
    Aykut Üren
    Mikell Paige
    Giuseppe Giaccone
    Maria Laura Avantaggiati
    Cell Death & Differentiation, 2018, 25 : 1239 - 1258
  • [9] Targeting of the mitochondrial citrate carrier (SLC25A1) lowers antioxidant defense systems and increases radiosensitivity of hypoxic cancer cells
    Hlouschek, J.
    Hansel, C.
    Jendrossek, V
    Matschke, J.
    STRAHLENTHERAPIE UND ONKOLOGIE, 2018, 194 : S30 - S30
  • [10] Inhibition of the mitochondrial citrate carrier, Slc25a1, reverts steatosis, glucose intolerance, and inflammation in preclinical models of NAFLD/NASH
    Mingjun Tan
    Rami Mosaoa
    Garrett T. Graham
    Anna Kasprzyk-Pawelec
    Shreyas Gadre
    Erika Parasido
    Olga Catalina-Rodriguez
    Patricia Foley
    Giuseppe Giaccone
    Amrita Cheema
    Bhaskar Kallakury
    Chris Albanese
    Chunling Yi
    Maria Laura Avantaggiati
    Cell Death & Differentiation, 2020, 27 : 2143 - 2157