Copper(<sc>i</sc>)-catalyzed coupling of alkynyl glycosides: synthesis of buta-1,3-diyne-linked disaccharides and dinucleosides

被引：0
|
作者：
Banday, Junaid Shafi [1 ,2 ]
Ahmed, Sajjad [1 ,2 ]
Ahmed, Qazi Naveed [1 ,2 ]
机构：
[1] CSIR Indian Inst Integrat Med, Nat Prod & Med Chem Div, Jammu 180001, India
[2] Acad Sci & Innovat Res AcSIR, Ghaziabad 201002, India
来源：
ORGANIC & BIOMOLECULAR CHEMISTRY | 2025年 / 23卷 / 11期
关键词：
POLYACETYLENES; CANCER;
D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Herein we report copper-catalyzed coupling of alkynyl glycosides facilitating the synthesis of buta-1,3-diyne-linked disaccharides. The reaction is characterized by mild conditions employing eco-friendly reagents, resulting in good yields of the desired products. This methodology exhibits significant functional group tolerance with broad substrate scope. Furthermore, we have successfully extended this approach to the synthesis of buta-1,3-diyne-linked dinucleosides.
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收藏
页码：2615 / 2619
页数：5
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