Dysregulation of endogenous retroviruses triggers aging and senescenceEndogenous retroviruses

被引：0
|
作者：
Jill A. Kreiling [1 ]
机构：
[1] Brown University,Department of Molecular Biology, Cell Biology, and Biochemistry, Center on the Biology of Aging
来源：
Nature Aging | 2024年 / 4卷 / 12期
关键词：
D O I：
10.1038/s43587-024-00759-0
中图分类号：
学科分类号：
摘要：
A study by Mao, Zhang, Zhuang and colleagues defines a specific class of endogenous retroviruses that are upregulated with age and in cellular senescence by the stress-induced transcription factor ATF3. The expression of endogenous retroviral elements has implications for the development of inflammation that may drive the onset of aging pathologies.
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页码：1670 / 1672
页数：2
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