An innovative glutamine metabolism-related gene signature for predicting prognosis and immune landscape in cervical cancer

被引：0
|
作者：
Hai-Ya Fang [1 ]
Li-Mei Ji [1 ]
Cui-Hua Hong [2 ]
机构：
[1] Jinhua Municipal Central Hospital,Department of Obstetrics and Gynecology
[2] Wenzhou Central Hospital,Department of Obstetrics and Gynecology
来源：
Discover Oncology | / 16卷 / 1期
关键词：
Glutamine metabolism; Cervical cancer; Prognosis; Risk score;
D O I：
10.1007/s12672-025-02109-x
中图分类号：
学科分类号：
摘要：
Four glutamine metabolism-related genes, UCP2, LEPR, TFRC, and RNaseH2A, were identified, and a novel risk assessment model was successfully developed.The Kaplan–Meier curve results indicated that the low-risk group had favorable prognostic outcomes.The expression levels of the signature genes were significantly negatively correlated with the infiltration of most immune cells.
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