HNRNPC modulates PKM alternative splicing via m6A methylation, upregulating PKM2 expression to promote aerobic glycolysis in papillary thyroid carcinoma and drive malignant progression (vol 22, 914, 2024)

被引:0
|
作者
Rong, Shikuo [1 ,2 ,4 ]
Dai, Bao [1 ,2 ]
Yang, Chunrong [3 ]
Lan, Ziteng [2 ]
Wang, Linhe [2 ]
Xu, Lei [1 ,2 ]
Chen, Weijian [2 ]
Chen, Jian [2 ]
Wu, Zeyu [1 ,2 ]
机构
[1] Guangdong Acad Med Sci, Guangdong Prov Peoples Hosp, Guangdong Cardiovasc Inst, Guangzhou, Guangdong, Peoples R China
[2] Southern Med Univ, Guangdong Prov Peoples Hosp, Guangdong Acad Med Sci, Dept Thyroid & Hernia Surg, Guangzhou, Guangdong, Peoples R China
[3] Hosp Chengdu Univ Tradit Chinese Med, Dept Gastroenterol, Chengdu, Sichuan, Peoples R China
[4] Southern Univ Sci & Technol, Jinan Univ, Shenzhen Peoples Hosp, Affiliated Hosp 1,Dept Thyroid Surg,Clin Med Coll, Shenzhen, Guangdong, Peoples R China
关键词
D O I
10.1186/s12967-025-06130-0
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
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页数:2
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  • [1] HNRNPC modulates PKM alternative splicing via m6A methylation, upregulating PKM2 expression to promote aerobic glycolysis in papillary thyroid carcinoma and drive malignant progression
    Rong, Shikuo
    Dai, Bao
    Yang, Chunrong
    Lan, Ziteng
    Wang, Linhe
    Xu, Lei
    Chen, Weijian
    Chen, Jian
    Wu, Zeyu
    JOURNAL OF TRANSLATIONAL MEDICINE, 2024, 22 (01)