Exploring cost reduction strategies for serum free media development

被引：1

作者：

Quek, Jun Ping ^{[1
]}

Gaffoor, Azra Anwar ^{[1
]}

Tan, Yu Xuan ^{[1
]}

Tan, Tessa Rui Min ^{[1
]}

Chua, Yu Feng ^{[1
]}

Leong, Dawn Sow Zong ^{[1
]}

Ali, Alif Sufiyan ^{[1
]}

Ng, Say Kong ^{[1
]}

机构：

[1] ASTAR, Bioproc Technol Inst BTI, 20 Biopolis Way,06-01 Centros, Singapore 138668, Singapore

来源：

NPJ SCIENCE OF FOOD | 2024年 / 8卷 / 01期

基金：

新加坡国家研究基金会;

关键词：

CELL-CULTURE MEDIUM; GROWTH; PROTEIN; LACTATE; SUBSTITUTION; METABOLISM; GLUTAMINE; PYRUVATE; AMMONIA; REUSE;

D O I：

10.1038/s41538-024-00352-0

中图分类号：

TS2 [食品工业];

学科分类号：

0832 ;

摘要：

Cultivated meat production offers solutions in addressing global food security and sustainability challenges. However, serum-free media (SFM) used in cultivating the cells are expensive, contributing to at least 50% of variable operating costs. This review explores technologies for cost-effective SFM, focusing on reducing cost from using growth factors and recombinant proteins, using affordable raw materials for basal media, and implementing cost-saving measures like media recycling and reducing waste build-up.

引用

页数：10

共 50 条

[1] STRATEGIES FOR OPTIMIZING SERUM-FREE MEDIA
HEWLETT, G
CYTOTECHNOLOGY, 1991, 5 (01) : 3 - 14
[2] Screening strategies for iron chelators in serum free media
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[3] The role of recombinant proteins in the development of serum-free media
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[4] In vitro development of Cryptosporidium parvum in serum-free media
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[5] The role of recombinant proteins in the development of serum-free media
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[6] Serum-free media products - Concerns over contaminants in serum drive tissue culture media development
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GENETIC ENGINEERING NEWS, 1998, 18 (12): : 28 - +
[7] DEVELOPMENT OF SERUM-FREE CELL CULTURE MEDIA FOR GENERAL USE
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IN VITRO-JOURNAL OF THE TISSUE CULTURE ASSOCIATION, 1971, 6 (05): : 380 - &
[8] Development of serum-free media for the culture and transfer of human blastocysts
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[9] Exploring cost-effective strategies for emission reduction of public buildings in a life-cycle
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[10] Serum-free media and serum alternatives
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TOXICOLOGY LETTERS, 2017, 280 : S81 - S81

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