Competition between homologous chromosomal DNA and exogenous donor DNA to repair CRISPR/Cas9-induced double-strand breaks in Aspergillus  niger

被引:0
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作者
Selina Forrer [1 ]
Mark Arentshorst [1 ]
Prajeesh Koolth Valappil [1 ]
Jaap Visser [1 ]
Arthur F. J. Ram [1 ]
机构
[1] Leiden University,Institute Biology Leiden, Microbial Sciences, Fungal Genetics and Biotechnology
关键词
CRISPR/Cas9 genome editing; Cell factory; Multicopy strains; DNA repair; Protein production;
D O I
10.1186/s40694-024-00184-3
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