Pediatric Society of the African League Against Rheumatism juvenile idiopathic arthritis recommendations for enthesitis-related arthritis and juvenile psoriatic arthritis

被引：0

作者：

Wafa Hamdi ^{[1
]}

Angela Migowa ^{[2
]}

Hanene Lassoued Ferjani ^{[1
]}

Chafia Dahou Makhloufi ^{[3
]}

Yasmine Makhlouf ^{[4
]}

Samah Ismail Nasef ^{[5
]}

Nelly Ziade ^{[6
]}

Xenophone Baraliakos ^{[7
]}

Hermine Brunner ^{[8
]}

Mohammed Hassan ^{[9
]}

Temesgen Libe ^{[10
]}

Elisa Palalane ^{[11
]}

Waleed Hassan ^{[12
]}

Ali Sobh ^{[13
]}

Ahmed Seri ^{[14
]}

Doaa Mosad ^{[15
]}

Hanna Lishan ^{[16
]}

Yassmin Taha ^{[17
]}

Ourida Gacem ^{[18
]}

Soad Hashed ^{[19
]}

Francis Fredrick Furia ^{[20
]}

Samy Slimani ^{[21
]}

Christiaan Scott ^{[22
]}

Djohra Hadef ^{[23
]}

机构：

[1] Kassab Institute,Department of Rheumatology, Faculty of Medicine of Tunis

[2] Tunis El Manar University,Department of Pediatrics

[3] Aga Khan University Medical College East Africa,Department of Rheumatology, Faculty of Medicine of Algiers

[4] Nairobi,Department of Rheumatology, Tunis El Manar University Faculty of Medicine of Tunis

[5] Med Lamine Debaghine University Hospital,Department of Rheumatology, Faculty of Medicine

[6] Mongi Slim Hospital,Rheumatology Department

[7] Suez Canal University,Division of Rheumatology, Department of Pediatrics, Cincinnati Children’s Hospital Medical Center

[8] Saint Joseph University and Hotel-Dieu De France,Rheumatology Department, Faculty of Medicine

[9] Rheumazentrum Ruhrgebiet,College of Health and Medical Sciences

[10] Ruhr University Bochum,Rheumatology and Rehabilitation Department

[11] University of Cincinnati College of Medicine,Department of Pediatrics

[12] Tanta University,Clinical Immunology and Allergy Center

[13] Haramaya University,Clinical Immunology and Allergy Department

[14] Hospital Central de Maputo,Department of Rheumatology and Rehabilitation

[15] Benha University,Rheumatology Unit, Department of Pediatrics and Child Health

[16] Mansoura University Children’s Hospital,Pediatric Rheumatology Unit

[17] Mansoura University Faculty of Medicine,Algiers Faculty of Medicine, Department of Pediatrics

[18] Royal Care International Hospital,School of Clinical Medicine

[19] Soba University Hospital,Pediatric Rheumatology

[20] Mansoura University Hospitals,Department of Pediatrics

[21] Mansoura University Faculty of Medicine,undefined

[22] College of Health Sciences,undefined

[23] Addis Ababa University,undefined

[24] Ahmed Gasim Children Hospital,undefined

[25] El Biar Hospital Algiers,undefined

[26] Tripoli Children’s Hospital,undefined

[27] University of Tripoli,undefined

[28] Muhimbili University of Health and Allied Sciences,undefined

[29] Atlas Clinic of Rheumatology,undefined

[30] University of Ottawa,undefined

[31] University of Cape Town,undefined

[32] University Hospital Center of Batna Faculty of Medicine,undefined

[33] Batna 2 University,undefined

来源：

Clinical Rheumatology | 2025年 / 44卷 / 3期

关键词：

Africa; Enthesitis-related arthritis; Juvenile idiopathic arthritis; Juvenile psoriatic arthritis; PAFLAR; Recommendations;

D O I：

10.1007/s10067-025-07334-x

中图分类号：

学科分类号：

摘要：

The objective of this study is to develop evidence-based recommendations for the diagnosis and management of enthesitis-related arthritis (ERA) and juvenile psoriatic arthritis (JPsA) in the African context. The recommendations for ERA and JPsA were combined into a single document. The steering committee and task force identified 15 key questions and formulated 35 research questions. A comprehensive literature review, utilizing Medline and a manual search for African local data, was conducted to gather evidence. Following this synthesis, the task force developed draft recommendations and engaged in a Delphi process with an expert panel, including 17 African and three international experts, to reach a consensus and ensure alignment with global standards. The final recommendations were assigned a level of evidence and subsequently approved by the task force members, the expert panel, and the PAFLAR Board. Fifteen recommendations on the diagnosis and management of ERA and JPsA were developed, covering the role of the pediatric rheumatologist in multiple aspects of disease management, including diagnosis, monitoring of disease and extra-articular manifestations, determining treatment strategies, and guiding interventions. The level of evidence supporting these recommendations was variable, leading to the identification of a research agenda to address African particularities and answer pending questions. The final recommendations achieved a high level of agreement, with consensus ranging from 90 to 100%. These recommendations represent an important achievement for pediatric rheumatology in Africa, being the first of their kind, tailored specifically to the region. Developed through a rigorous methodology and collaboration between international and African experts, they aim to standardize care and address the unique challenges faced in African setting.

引用

页码：901 / 922

页数：21

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