A water-soluble Gd(<sc>iii</sc>)-based fluorescence/T1-MR dual-modality probe for H2S sensing

被引：0

作者：

Mak, Ho-Nam ^{[1
]}

Lu, Xuanyi ^{[2
]}

Pan, Siyu ^{[2
]}

Gu, Yanjuan ^{[1
]}

Jiang, Lijun ^{[1
,2
]}

Wong, Wing-Tak ^{[1
]}

机构：

[1] Hong Kong Polytech Univ, Dept Appl Biol & Chem Technol, Hong Kong, Peoples R China

[2] Cent China Normal Univ, Sch Life Sci, Hubei Key Lab Genet Regulat & Integrat Biol, Key Lab Pesticide & Chem Biol,Minist Educ, Wuhan 430079, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2024年 / 60卷 / 97期

基金：

中国国家自然科学基金;

关键词：

HYDROGEN-SULFIDE; RELAXIVITY;

D O I：

10.1039/d4cc05042h

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We present a water-soluble fluorescence/MR dual-modality probe NBD[Gd] for H2S detection. It showed 88.4% of fluorescence quenching and a 36% reduction in r1 upon exposure to H2S. It is readily uptaken by cells to sense the endogenous H2S. Besides providing a bimodal H2S imaging probe, our study also confirms the high H2S level in CT26 cells and its functional consequence in promoting cell growth.

引用

页码：14419 / 14422

页数：4

共 16 条

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