Electrochemical sensor based on conjugated microporous polymer for sensitive detection of epinephrine

A novel reduced graphene-based conjugated microporous polymer（CMP-rGO）material was prepared by Sonogashira-Hagihara coupling method. The morphology and structure of CMP-rGO were characterized by scanning electron microscopy （SEM），transmission electron microscopy （TEM），Fourier transform infrared spectroscopy （FT-IR），and X-ray photoelectron spectroscopy （XPS）. The electrochemical properties of CMP-rGO material were researched by electrochemical impedance spectroscopy （EIS）and cyclic voltammetry （CV）. And the prepared materials were applied to the construction of epinephrine （EP）electrochemical sensors. The results showed the CMP-rGO modified electrode exhibited good electrical conductivity and electrocatalytic activity. Under the optimum conditions，the oxidation current of EP showed a good linear relationship with its concentration in the range of 0.08-80 µμmol/L，with a detection limit of 6.741 nmol/L. Therefore，electrochemical sensors based on CMP-rGO can be applied to clinical disease diagnosis. © 2024, Youke Publishing Co.,Ltd. All rights reserved.