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A Self-Assembled Nano-Molecular Glue (Nano-mGlu) Enables GSH/H2O2-Triggered Targeted Protein Degradation in Cancer Therapy
被引:0
|作者:
Sun, Jie
[1
,6
]
Gu, Mingxi
[1
]
Peng, Lvyang
[1
]
Guo, Jing
[3
]
Chen, Peng
[1
,2
]
Wen, Yalei
[3
]
Feng, Fang
[4
]
Chen, Xiaojuan
[5
]
Liu, Tongzheng
[3
]
Chen, Yongheng
[5
]
Lu, Xiaoyun
[3
]
Gao, Liqian
[1
]
Yao, Shao Q.
[2
]
Yuan, Peiyan
[1
]
机构:
[1] School of Pharmaceutical Sciences (Shenzhen), Shenzhen Campus of Sun Yat-Sen University, Shenzhen,518107, China
[2] Department of Chemistry, National University of Singapore, Singapore,117543, Singapore
[3] State Key Laboratory of Bioactive Molecules and Druggability Assessment, International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Discovery, Chinese Ministry of Education, School of Pharmacy, Jinan University,
[4] Division of Antitumor Pharmacology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai,201203, China
[5] Department of Oncology, NHC Key Laboratory of Cancer Proteomics, State Local Joint Engineering Laboratory for Anticancer Drugs, Xiangya Hospital, Central South University, Changsha,410008, China
[6] Department of Pharmacy, Linyi People’s Hospital, Linyi,276000, China
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