Prostaglandin synthesis inhibitor improves hypotension during cardiopulmonary bypass

被引：0
|
作者：
Takewa, Y. [1 ]
Seki, T. [1 ]
Tatsumi, E. [2 ]
Taenaka, Y. [2 ]
Takano, H. [2 ]
机构：
[1] Nara Prefectural Mimuro Hospital
[2] National Cardiovascular Center, Japan
来源：
ASAIO Journal | 2000年 / 46卷 / 02期
关键词：
Biosynthesis - Blood - Cardiovascular surgery - Drug dosage - Drug infusion - Hemodynamics - Urology;
D O I：
10.1097/00002480-200003000-00049
中图分类号：
学科分类号：
摘要：
In this study, an attempt was made to investigate whether prostaglandin (PG) synthesis inhibitor (PGSI) can improve hypotension during cardiopulmonary bypass (CPB). The mean systemic blood pressure (SBP), the blood base excess (BE), the urine output and the dose of metaraminol were estimated. Administration of PGSI during CPB improved hypotension and increased urine output without impairing peripheral circulation.
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