Bone cell adhesion on titanium implants with nanoscale surface features

被引：0
|
作者：
Ejiofor, Jeremiah U. [1 ]
Webster, Thomas J. [1 ]
机构：
[1] Biomedical Engineering, Purdue University, Dept. of Biomedical Engineering, 500 Central Drive, West Lafayette, IN 47907, United States
来源：
International Journal of Powder Metallurgy (Princeton, New Jersey) | 2004年 / 40卷 / 02期
关键词：
Adhesion - Biocompatibility - Bone - Grain size and shape - Microscopic examination - Nanostructured materials - Particle size analysis - Substrates - Titanium;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The topography and morphology of participate Ti-6AL-4V and ASTM Grade II Ti were investigated in relation to their effects on cellular functions in orthopedic applications. Osteoblasts (bone-forming cells) were seeded onto substrates in order to assess the influence of particle size, particle shape and substrate grain size on cytocompatibility. Cells were cultured before seeding and were fixated and stained after adhesion and proliferation bioactivities. Fluorescent microscopy was utilized for cell counting and the mechanisms of adhesion were determined by scanning electron microscopy. Observations confirm the potential of submicron particles or nanoparticles in improving the biocompatibility of titanium implants.
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页码：43 / 53
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