Interactive determination of the parameters of mathematical models for planning radiation therapy for malignant tumors. Part 3. Method of local adjustment of the parameters of mathematical models (examples of application)

被引：0

作者：

Klepper, L.Ya. ^{[1
]}

机构：

[1] Ts. Ekonomiko-Matematicheskij Inst., RAN, Moscow, Russia

来源：

Meditsinskaya Tekhnika | 2001年 / 01期

关键词：

Malignant tumors - Radiotherapy planning;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

To increase the accuracy of calculation of tolerance doses of the likelihood of radiation-induced complications in normal organs and tissues by using mathematical models, the author has developed a method for local mathematical model parameter adjustment (LMMPA) which included analysis of the structure of a mathematical model, systematization of clinical information and its use to determine the parameters of a model. LMMPA may be regarded as the interactive determination of their parameters that describing radiation exposures of complex biological systems. Different aspects of using of LMMPA are indicated how to apply it to the determination of tolerance doses for connective tissue, lung tissue, and the brain by using the Ellis and LQ models.

引用

页码：27 / 33

共 10 条

[1] Interactive determination of parameters of mathematical models for planning of radiation therapy of malignant tumors. Part 3. Several applications of the method of local tuning of mathematical model parameters
Klepper La.Y.
Biomedical Engineering, 2001, 35 (1) : 29 - 36
[2] Interactive determination of parameters of mathematical models for planning of radiation therapy of malignant tumors. Part 2. Method of local tuning of mathematical model parameters for calculating tolerant doses and probability of post-radiation complications in normal organs and tissues of the human body
Klepper L.Ya.
Biomedical Engineering, 2000, 34 (5) : 268 - 271
[3] Interactive determination of the parameters of mathematical models used for planning of radiation therapy of malignant tumors. Part 1. Mathematical models for calculating the tolerant doses, adequate doses, and the probability of post-radiation complications in normal organs and tissues
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Biomedical Engineering, 2000, 34 (4) : 207 - 212
[4] Aggregation method for determination of parameters of mathematical models
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Biomedical Engineering, 2008, 42 (1) : 32 - 36
[5] Software package for planning fractionated schemes of irradiation of malignant tumors using local tuning of parameters of mathematical models
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Biomedical Engineering, 1998, 32 (2) : 64 - 68
[6] Programmed complex for planning fractionated malignant tumor radiation regimens by local adjustment of mathematical model parameters
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Meditsinskaya Tekhnika, 1998, (02): : 7 - 10
[7] Mathematical simulation of optimal dose fields in radiation therapy of malignant tumors. Part 1. Remote radiation therapy
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Biomedical Engineering, 2004, 38 (1) : 34 - 41
[8] Mathematical simulation of optimal dose fields in radiation therapy of malignant tumors. Part 2. Contact methods of radiation therapy
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[9] CROSSBREEDING IN FARM-ANIMALS .3. A GENERAL-METHOD OF COMPARING MODELS TO ESTIMATE CROSSBREEDING PARAMETERS WITH AN APPLICATION TO DIALLEL CROSSBREEDING EXPERIMENTS
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[10] Experimental designs applied to hydrothermal synthesis of zeolite ERI plus OFF (T) in the Na2O-K2O-Al2O3-SiO2-H2O system Part 3.: Mathematical models and geometrical forms of the relationship between product properties and synthesis parameters:: an attempt to optimize synthesis conditions
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