Effects of Hg(C104)2, HgC12, and AgC104 on the conformations of poly-(S-carboxymethyl-L-cysteine) and Poly[S-(2-carboxyethyl)-L-cysteine] in Solution

被引：0

作者：

Oka, Kazuki ^{[1
]}

Maeda, Hiroshi ^{[1
]}

Ikeda, Shoichi ^{[1
]}

机构：

[1] Department of Chemistry, Faculty of Science, Nagoya University, Chikusa-ku, Nagoya,464, Japan

来源：

Bulletin of the Chemical Society of Japan | 1984年 / 57卷 / 06期

关键词：

Silver halides - Dichroism - Amino acids - Chlorine compounds;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

The effects of Hg(C104)2, HgC12, and AgC104 on the conformations of fully neutralized poly(S-carboxymethyl-l-cysteine) and poly[S-(2-carboxyethyl)-l-cysteine] in the absence of supporting electrolytes were examined by circular dichroism (CD) spectra. The induction of the /3-form was suggested by the addition of Hg(C104)2 and AgC104, while it could not be concluded in the case of HgCl2. Spectroscopic evidence for the coordination of metals with the two polypeptides was provided in the case of Hg(C104)2 and HgCl2 by the appearance of a new CD band around 250-260 nm as well as the distortion of the polymer CD spectra in the region of 200-230 nm, while it was not obtained in the case of AgClp4. The decrease of pH observed on addition of the three metal compounds also suggested the conformational change. Extraordinary lowering of pH and enhanced solubility were observed on addition of HgCl2. © 1984 The Chemical Society of Japan.

引用

页码：1473 / 1477

共 13 条

[1] EFFECTS OF HG(CLO4)2, HGCL2, AND AGCLO4 ON THE CONFORMATIONS OF POLY-(S-CARBOXYMETHYL-L-CYSTEINE) AND "POLY[S-(2-CARBOXYETHYL)-L-CYSTEINE] IN SOLUTION
OKA, K
MAEDA, H
IKEDA, S
BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, 1984, 57 (06) : 1473 - 1477
[2] Structural and Functional Studies of S-(2-Carboxyethyl)-L-Cysteine and S-(2-Carboxyethyl)-l-Cysteine Sulfoxide
Waters, James K.
Mossine, Valeri V.
Kelley, Steven P.
Mawhinney, Thomas P.
MOLECULES, 2022, 27 (16):
[3] INTERACTION OF "POLY[S-(2-CARBOXYETHYL)-L-CYSTEINE] WITH CATIONIC SURFACTANTS
MAEDA, H
TANAKA, Y
IKEDA, S
BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, 1986, 59 (03) : 769 - 773
[4] INDUCTION OF THE BETA-FORM OF POLY(S-CARBOXYMETHYL-L-CYSTEINE) AND "POLY[S-(2-CARBOXYETHYL)-L-CYSTEINE] BY CHROMIUM(III), IRON(III), AND LANTHANUM(III) CHLORIDES
OKA, K
MAEDA, H
IKEDA, S
BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, 1984, 57 (03) : 696 - 700
[5] ABSORPTION AND CIRCULAR-DICHROISM SPECTRA OF CUCL2 COMPLEXED WITH POLY(S-CARBOXYMETHYL-L-CYSTEINE) AND POLY(S-CARBOXYETHYL-L-CYSTEINE)
MAEDA, H
OKA, K
IKEDA, S
BIOPOLYMERS, 1985, 24 (07) : 1115 - 1129
[6] CONFORMATION OF POLY(S-(2-N-CARBAZOLYLETHYL)-L-CYSTEINE) IN THE SOLID-STATE
OSHIMA, R
WADA, T
KUMANOTANI, J
JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY, 1984, 22 (09) : 2047 - 2059
[7] SYNTHESIS OF POLY[S-(2-9'-ACRIDINYLETHYL)-L-CYSTEINE] AND ITS TCNQ SALT
OSHIMA, R
SATO, T
KUMANOTANI, J
JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY, 1985, 23 (03) : 787 - 793
[8] Improved ε-poly-L-lysine production of an S-(2-aminoethyl)-L-cysteine resistant mutant of Streptomyces albulus
Hiraki, J
Hatakeyama, M
Morita, H
Izumi, Y
SEIBUTSU-KOGAKU KAISHI, 1998, 76 (12): : 487 - 493
[9] EFFECTS OF CHAIN-LENGTH AND CONCENTRATION ON THE BETA-COIL CONVERSION OF POLY[S-(CARBOXYMETHYL)-L-CYSTEINE] IN 50 MM NACL SOLUTIONS
MAEDA, H
GATTO, Y
IKEDA, S
MACROMOLECULES, 1984, 17 (10) : 2031 - 2038
[10] Naphthyl-Poly(S-((2-carboxyethyl)thio)-L-cysteine) Peptide Amphiphiles with Different Degrees of Polymerization: Synthesis, Self-Assembly, pH/Reduction-Triggered Drug Release, and Cytotoxicity
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MOLECULAR PHARMACEUTICS, 2023, 20 (02) : 1256 - 1268

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