TECHNIQUES FOR SCALE-UP TO PROCESS HPLC.

被引:0
|
作者
Dwyer, James L. [1 ]
机构
[1] Millipore Corp, MA, USA, Millipore Corp, MA, USA
来源
Kemia-Kemi/Finnish Chemical Journal | 1985年 / 12卷 / 03期
关键词
CHROMATOGRAPHIC ANALYSIS;
D O I
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中图分类号
学科分类号
摘要
The purpose of this paper is to describe the techniques used in determining feasibility of a process HPLC separation and the actual scale-up from milligram quantities to multi-kilogram operations. The author has found it practical to be able to accurately estimate the performance of large scale process HPLC equipment on the basis of experiments done with conventional analytical HPLC instrumentation.
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页码:247 / 251
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