Two unusual cases of acute digoxin intoxication caused by accidental mistaken

被引：0
|
作者：
Chen, S.-C. [1 ]
Jiao, S. [1 ]
He, G.-W. [1 ]
Lu, D.-H. [1 ]
Li, X.-H. [1 ]
Guo, M.-Y. [1 ]
机构：
[1] Department of Pharmacy, Luhe Hospital, Beijing 101149, China
来源：
| 2001年 / Chinese Medical Association卷 / 36期
关键词：
Concentration; (process); -; Electrocardiography; Potassium; Toxicity;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
OBJECTIVE: To observe the toxic manifestations of digoxin (DGX) in two children after orally overdose of DGX. METHODS: The clinical toxic symptoms and signs were observed. At the same time, the concentrations of DGX and potassium in serum were determined, the electrocardiogram (ECG) was recorded. RESULTS: After orally taking an overdose of DGX, the children showed continual vomiting, anorexia, fatigue, somnolence etc. Heart toxicity displayed brady arrhythmias: sinus standstill, sinoauricular block or atrioventricular block. The higher serum DGX concentration was, the worse its toxicity was. It was obvious that the above symptoms eased off while the serum DGX concentration decreased. When serum DGX concentration was below 3.0 μg &middot L-1, the above symptoms were almost disappeared. CONCLUSION: The acute toxicity of DGX in two children was mostly related to the systems of digestion, CNS and circulation. It showed especially heart toxicity and closely correlative with the serum DGX concentration.
引用
收藏
相关论文
共 50 条
  • [1] 2 CASES OF ACUTE ACCIDENTAL INTOXICATION BY DISULFONE
    MARTIN, C
    BABIN, JP
    DEMARQUE.JL
    ALLAIN, D
    NKIDIAKA
    ROSSIGNO.
    AUTHIER, F
    ARCHIVES FRANCAISES DE PEDIATRIE, 1974, 31 (08): : 831 - 831
  • [2] Be(a)ware of the fentanyl patch: unusual accidental cases of fentanyl intoxication
    Leenders, Marianne E. E.
    Visser, Corine C.
    de Lange, Dylan W.
    CLINICAL TOXICOLOGY, 2020, 58 (06) : 614 - 614
  • [3] ABOUT 28 CASES OF ACUTE COLLECTIVE AND ACCIDENTAL INTOXICATION WITH TRICHLORETHYLENE
    MOUTON, N
    ARCHIVES DES MALADIES PROFESSIONNELLES DE MEDECINE DU TRAVAIL ET DE SECURITE SOCIALE, 1972, 33 (1-2): : 66 - &
  • [4] Two cases of acute mercurial intoxication
    Morlot
    Zuber
    COMPTES RENDUS DES SEANCES DE LA SOCIETE DE BIOLOGIE ET DE SES FILIALES, 1914, 76 : 896 - 898
  • [5] Two Cases of Digoxin Intoxication: Insights into ECG Findings and Visual Disturbances
    Engindeniz, Zulfi
    Nallar, Busra
    Dayi, Muhammed
    JOURNAL OF EMERGENCY MEDICINE CASE REPORTS, 2024, 15 (01): : 16 - 18
  • [6] Two unusual cases of plant intoxication in small ruminants
    Baert, K
    Croubels, S
    Steurbaut, N
    De Boever, S
    Vercauteren, G
    Ducatelle, R
    Verbeken, A
    De Backer, P
    VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT, 2005, 74 (02): : 149 - 153
  • [7] An unusual intoxication by hyoscyamus albus:: About two cases
    Hamouda, C.
    Ghorbal, H.
    Cherni, K.
    Allouche, M.
    Moklin, A.
    Hedhili, A.
    Amamou, M.
    TOXICOLOGY LETTERS, 2005, 158 : S232 - S232
  • [8] An Unusual Case of Accidental Carbon Monoxide and Ethanol Intoxication in Two Commorientes Deaths
    Dumbrava, Dan Perju
    Radu, Carmen Corina
    Iov, Tatiana
    Damian, Simona Irina
    Sandu, Ion
    Timofte, Daniel
    Chiroban, Ovidiu
    REVISTA DE CHIMIE, 2018, 69 (07): : 1889 - 1891
  • [9] Acute pulmonary edema caused by accidental aspiration of sweetened water in two cases of diabetes mellitus
    Kaneki, T
    Kubo, K
    Sone, S
    Kawashima, A
    INTERNAL MEDICINE, 1998, 37 (11) : 969 - 972
  • [10] Acute bilateral blindness caused by accidental methanol intoxication during fire "eating"
    Cursiefen, C
    Bergua, A
    BRITISH JOURNAL OF OPHTHALMOLOGY, 2002, 86 (09) : 1064 - 1065
12345