Synthesis and characterization of 2, 7-dibromospiro [fluorene-9, 9'-(2', 7'-dihydroxy-1', 8'-disulfonic-xanthene)]

被引：0

作者：

Wang L.-Y. ^{[1
]}

Song Y.-J. ^{[1
]}

Cao D.-R. ^{[1
]}

机构：

[1] School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510640, Guangdong

来源：

Huanan Ligong Daxue Xuebao/Journal of South China University of Technology (Natural Science) | 2010年 / 38卷 / 09期

关键词：

Fluorene; Spiro; Sulfonation; Synthesis; Yield;

D O I：

10.3969/j.issn.1000-565X.2010.09.014

中图分类号：

学科分类号：

摘要：

First, 2, 7-dibromospiro[fluorene-9, 9'-(2', 7'-dihydroxy-xanthene)] (Compound III) was prepared through such three steps as Br2/Fe bromination, CrO3/Ac2O oxidation and resoreinol/ZnCl2 catalytic condensation, with fluorene as the starting material. Then, 2, 7-dibromospiro[fluorene-9, 9'-(2', 7'-dihydroxy-1', 8'-disulfonic-xanthene)] (Compound IV) was synthesized via the sulfonation of Compound III with concentrated sulfuric acid and was characterized by means of IR, 1H NMR and UV-Vis, etc. Finally, the effects of reaction temperature, reactant molar ratio and reaction time on the sulfonation yield were investigated, and the optimal reaction conditions for Compound IV with a yield up to 86.5% were determined, that is, adding 1 g of Compound III together with 3 mL concentrated sulfuric acid for the sulfonation at 70°C for 2 h.

引用

页码：75 / 79

页数：4

共 9 条

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