Laxative Effect of Black Garlic on Constipation Mice

被引:0
|
作者
Lu X. [1 ]
Tian J. [1 ]
Li N. [1 ]
Qiu Z. [1 ]
Qiao X. [1 ]
机构
[1] College of Food Science and Engineering, Shandong Agricultural University, Tai'an, 271000, Shandong
关键词
Black garlic; Constipation; Laxative function; Mice;
D O I
10.16429/j.1009-7848.2019.12.006
中图分类号
学科分类号
摘要
Objective: To investigate the effect of black garlic on lubricating bowel and on the defecation function of constipation mice. Methods: Kunming mice were randomly divided into control group, model control group, positive control group and low, medium- and high-dose treatment groups. After continuous intragastric administration for 7 days, through applying small intestinal propelling test and defecation test in mice to observe the effect of the black garlic, the percentage of propellant in small intestine, the time of the first dejection, the dejection amount and weights in six hours and the stool shape were observed. Results: All the tested parameters differed significantly between each dose of black garlic infusion and either the model group or the positive control group. It could apparently improve the percentage of propellant in intestinal peristalsis, shorten the time of the first black dejection, increase feces amount and weights in six hours and improve the water content of mice feces. Conclusion: The black garlic had the laxative effect in constipation mice. © 2019, Editorial Office of Journal of CIFST. All right reserved.
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页码:39 / 43
页数:4
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  • [1] Pare P., Ferrazzi S., Thompson W.G., Et al., An epidemiological survey of constipation in Canada: definitions, rates, demographics, and predictors of health care seeking, The American Journal of Gastroenterology, 96, 11, pp. 3130-3137, (2001)
  • [2] Barzilay J.I., Abraham L., Heckbert S.R., Et al., The relation of markers of inflammation to the development of glucose disorders in the elderly, Diabetes, 50, 10, pp. 2384-2389, (2001)
  • [3] Li N., Lu X., Pei H., Et al., Effect of freezing pretreatment on the processing time and quality of black garlic, Journal of Food Process Engineering, 38, 4, pp. 329-335, (2015)
  • [4] Sato E., Kohno M., Hamano H., Et al., Increased anti-oxidative potency of garlic by spontaneous short-term fermentation, Plant Foods for Human Nutrition, 61, 4, pp. 157-160, (2006)
  • [5] Kim D., Jung S.J., Cheon S.Y., Et al., Antioxidant activity of giant black garlic, Proceedings of the Nutrition Society, 72, (2013)
  • [6] Kim J.H., Nam S.H., Rico C.W., Et al., A comparative study on the antioxidative and anti-allergic activities of fresh and aged black garlic extracts, International Journal of Food Science & Technology, 47, 6, pp. 1176-1182, (2012)
  • [7] Wang D., Feng Y., Liu J., Et al., Black garlic (Allium sativum) extracts enhance the immune system, Medicinal and Aromatic Plant Science and Biotechnology, 4, 1, pp. 37-40, (2010)
  • [8] Kim I., Kim J.Y., Hwang Y.J., Et al., The beneficial effects of aged black garlic extract on obesity and hyperlipidemia in rats fed a high-fat diet, Journal of Medicinal Plants Research, 5, 14, pp. 3159-3168, (2011)
  • [9] Claude J., Ubbink J., Thermal degradation of carbohydrate polymers in amorphous states: A physical study including colorimetry, Food Chemistry, 96, 3, pp. 402-410, (2006)
  • [10] Zhang Z., Lei M., Liu R., Et al., Evaluation of alliin, saccharide contents and antioxidant activities of black garlic during thermal processing, Journal of Food Biochemistry, 39, 1, pp. 39-47, (2015)