Determinants of bisphenol A and phthalate metabolites in urine of Flemish adolescents

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作者
Geens, Tinne [1 ]
Bruckers, Liesbeth [2 ]
Covaci, Adrian [1 ]
Schoeters, Greet [3 ,4 ]
Fierens, Tine [3 ,5 ]
Sioen, Isabelle [5 ]
Vanermen, Guido [6 ]
Baeyens, Willy [7 ]
Morrens, Bert [8 ]
Loots, Ilse [8 ]
Nelen, Vera [9 ]
de Bellevaux, Benoit Nemery [10 ]
Larebeke, Nik Van [11 ]
Hond, Elly Den [3 ]
机构
[1] Toxicological Center, University of Antwerp, Belgium
[2] Interuniversity Institute for Biostatistics and Statistical Bioinformatics, Hasselt University, Belgium
[3] Environmental Risk and Health Unit, Flemish Institute for Technological Research (VITO), Belgium
[4] Department of Biomedical Sciences, University of Antwerp, Belgium
[5] Department of Public Health, Ghent University, Belgium
[6] Environmental Analysis and Technology Unit, Flemish Institute for Technological Research (VITO), Belgium
[7] Department of Analytical and Environmental Chemistry, Vrije Universiteit Brussel (VUB), Belgium
[8] Department of Sociology, University of Antwerp, Belgium
[9] Provincial Institute for Hygiene, Antwerp, Belgium
[10] Department of Public Health, Occupational and Environmental Medicine, University of Leuven, Belgium
[11] Department of Analytical and Environmental Chemistry, Vrije Universiteit Brussel (VUB), Ghent University, Belgium and (retired) Study Centre for Carcinogenesis and Primary Prevention of Cancer, Belgium
关键词
Adolescent - Biomonitoring - Bisphenol A - Bisphenols-A - Determinants of exposure - Flanders - Health-study - Household income - Phthalate metabolites - Phthalates;
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摘要
As part of the second Flemish Environment and Health Study (FLEHS II), bisphenol-A (BPA) and different phthalate metabolites were analyzed, for the first time, in the urine of 210 adolescents in Flanders, Belgium. All chemicals had a detection frequency above 90%. For all compounds, except the sum of DEHP, highest levels were detected during spring. Average values for the Flemish adolescents were in an agreement with concentrations found in different international studies, all confirming the ubiquity of BPA and phthalate exposure. There was a significant correlation between BPA and the different phthalate metabolites (r between 0.26 and 0.39; p
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页码:110 / 117
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