Unravelling the Synthesis of 2-Aminobenzo[d]thiazole Derivatives via a Novel Zinc(II)-Catalyzed Strategy

被引：0
|
作者：
Neetha, Mohan [1 ]
Umabharathi, S. B. [2 ]
Anilkumar, Gopinathan [1 ,3 ]
机构：
[1] Mahatma Gandhi Univ, Sch Chem Sci, Priyadarsini Hills, Kottayam 686560, Kerala, India
[2] Sch Phys Sci, Amrita Vishwa Vidyapeetham, Amritapuri Campus,Clappana PO, Kollam 690525, Kerala, India
[3] Mahatma Gandhi Univ, Inst Integrated Programmes & Res Basic Sci IIRBS, Priyadarsini Hills PO, Kottayam 686560, Kerala, India
来源：
CATALYSIS LETTERS | 2025年 / 155卷 / 01期
关键词：
2-Aminobenzothiazole; Et2Zn; 2-Bromophenyl isothiocyanate; Amines; C-S bond; C-N bond; Acetonitrile; CROSS-COUPLING REACTION; ARYL IODIDES; 2-AMINOBENZOTHIAZOLES; BENZOTHIAZOLE; CYCLIZATION; FORMAMIDES; INHIBITORS; CONVERSION; RILUZOLE;
D O I：
10.1007/s10562-024-04835-3
中图分类号：
O64 [物理化学（理论化学）、化学物理学];
学科分类号：
070304 ; 081704 ;
摘要：
The first zinc(II)-catalyzed approach towards an array of 2-aminobenzothiazole derivatives was successfully developed. In this process, the substrate 2-bromophenyl isothiocyanate was reacted with a range of amines, including aromatic and aliphatic (primary and secondary) and cyclic secondary amines, yielding the products in reasonably good amounts. The reactivity analyses of different amines revealed that cyclic secondary amines performed exceptionally well, providing excellent outcomes. Additionally, aliphatic amines also exhibited the capability to undergo the transformation successfully.
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页数：10
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