The importance of yarn structural variants such as spinning draft, twist factor, yarn structure, and spindle speed in deciding the hand-related characteristics of woven cotton fabrics has been investigated using FAST evaluation system. The data indicate that the processing differences of each yarn type confer different extensibility, bending rigidity and shear rigidity values, and the differences in the yarn structure affect the fabric formability and other low deformation characteristics. Effects obtained by changing twist factor and spinning draft are found to be significant; however, by using an optimum spinning draft and varying twist factor, one can successfully produce fabrics with low rigidities and quite sufficient extensibility and formability. The spindle speed does not seem to affect the coercive shear rigidity in either ring- or compact-spun yarn fabrics. The handle response of fabrics woven with compact-spun yarns is quite satisfactory in many respects.