Comprehensive evaluation method of real-time non-reference ultrasound image involving soft tissue deformation

超声引导的经皮介入治疗已在临床中得到了广泛应用。针对机器人辅助的超声引导治疗中探头接触力引起软组织形变的问题，提出一种考虑软组织形变的实时无参考超声图像综合评估方法。所提方法在超声图像亮度和锐度评估的基础上，融合组织或腺体的聚集特性设计了一种多维度的超声图像评价指标。为了验证所提方法的有效性，分别采集前列腺体模、内置囊肿的体模、猪肝脏组织，以及内置囊肿的猪肝脏组织4种不同模型的超声图像进行实验测试与分析，并基于斯皮尔曼秩相关系数分析了主客观评价的相关性。实验结果表明单幅图像的平均评估时间为68.8 ms，满足实时应用的需要。本文所提方法实现了机器人辅助治疗中实时超声图像的有效评估，并且评估结果与主观评价具有良好的一致性。.; Ultrasound guided percutaneous interventional therapy has been widely used in clinic. Aiming at the problem of soft tissue deformation caused by probe contact force in robot-assisted ultrasound-guided therapy, a real-time non-reference ultrasound image evaluation method considering soft tissue deformation is proposed. On the basis of ultrasound image brightness and sharpness, a multi-dimensional ultrasound image evaluation index was designed, which incorporated the aggregation characteristics of the organization. In order to verify the effectiveness of the proposed method, ultrasound images of four different models were collected for experiments, including prostate phantom, phantom with cyst, pig liver tissue, and pig liver tissue with cyst. In addition, the correlation between subjective and objective evaluations was analyzed based on Spearman's rank correlation coefficient. Experimental results showed that the average evaluation time of a single image was 68.8 milliseconds. The evaluation time could satisfy real-time applications. The proposed method realizes the effective evaluation of real-time ultrasound image quality in robot-assisted therapy, and has good consistency with the evaluation of supervisors.