Effect of Nano-hydroxyapatite on Degradability and in Vitro Bioactivity of Magnesium Oxychloride Cement

被引：0
|
作者：
Li H. [1 ]
Liao J. [1 ]
Mao Y. [1 ]
Ruan W. [1 ]
机构：
[1] School of Materials Science and Engineering, Henan Polytechnic University, Henan, Jiaozuo
来源：
Cailiao Daobao/Materials Reports | 2023年 / 37卷 / 24期
关键词：
bone cement; degradability; in vitro bioactivity; magnesium oxychloride cement; nano-hydroxyapatite; water resistance;
D O I：
10.11896/cldb.22020189
中图分类号：
学科分类号：
摘要：
Magnesium oxychloride cement(MOC)has the advantages of high strength,good adhesion and non-cytotoxicity,which can be applied in the field of bone repair materials. In this study,nano-hydroxyapatite (n-HAp),a bioactive material,was incorporated into MOC and the effects of n-HAp on water resistance,degradability and bioactivity of MOC were investigated. It was found that the best amount of n-HAp was 10% by mass of magnesium oxide. After soaking in simulated body fluid (SBF)for 28 d,the compressive strength ((29. 9±1. 8)MPa)and softening coefficient (0. 39)of 10% n-HAp-MOC were higher than those of the unmodified MOC,and the mass loss rate (34. 5%)was lower than that of the unmodified MOC. The addition of n-HAp enhanced the water resistance of MOC and thereby reduced effectively its degradation rate. Based on XRD analysis and ion concentration change,hydroxyapatite crystals could be deposited on the surface of MOC,indicating that MOC has biological activity. The incorporation of n-HAp promoted the growth of mineralized HAp crystals deposited on the surface of MOC and enhanced the bioactivity of MOC. © 2023 Cailiao Daobaoshe/ Materials Review. All rights reserved.
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